Mitochondria are key players in several cellular functions including growth, division, energy
metabolism, and apoptosis. The mitochondrial network undergoes constant remodelling and …

Alterations in oxidative phosphorylation resulting from mitochondrial dysfunction have long
been hypothesized to be involved in tumorigenesis. Mitochondria have recently been shown …

Mitochondria are dynamic intracellular organelles that play a central role in oxidative
metabolism and apoptosis. The recent resurgence of interest in the study of mitochondria …

Decades ago, Otto Warburg observed that cancers ferment glucose in the presence of
oxygen, suggesting that defects in mitochondrial respiration may be the underlying cause of …

Mitochondria are well known for their role in ATP production and biosynthesis of
macromolecules. Importantly, increasing experimental evidence points to the roles of …

Mitochondria play important roles in cellular energy metabolism, free radical generation, and
apoptosis. Defects in mitochondrial function have long been suspected to contribute to the …

Mitochondria are the cytoplasmic organelles mostly known as the “electric engine” of the
cells; however, they also play pivotal roles in different biological processes, such as cell …

Mitochondria play a central role not only in energy production but also in the integration of
metabolic pathways as well as signals for apoptosis and autophagy. It is becoming …

The better part of a century has passed since Otto Warburg first hypothesized that unique
phenotypic characteristics of tumor cells might be associated with an impairment in the …

Mitochondria have traditionally been viewed as the powerhouse of the cell, where they
serve, amongst other functions, as a major source of ATP generation. More recently …