Successful therapy and diagnosis of glioma is one of the biggest challenges in the
biomedical fields. The incidence is growing gradually around the world. Annually, there are …

Glioblastoma multiforme (GBM) is one of the most deadly diseases that affect humans, and it
is characterized by high resistance to chemotherapy and radiotherapy. Its median survival is …

Glioma is the most common and aggressive primary intracranial tumor within the central
nervous system. The blood–brain barrier (BBB) has been a great hurdle for an effective …

Given the limited sensitivity of screening methods and the lack of effective therapeutic
interventions for malignant brain tumors such as glioblastoma multiforme (also known as …

Brain tumors, especially the most prevalent and aggressive glioblastoma, remain among the
deadliest of all types of cancer due to inefficient theranostic options. They have a limited …

Glioblastoma is one of the most aggressive central nervous system malignancies with high
morbidity and mortality. Current clinical approaches, including surgical resection …

Glioblastoma multiforme (GBM), a grade IV astrocytoma as defined by the World Health
Organization (WHO) criteria, is the most common primary central nervous system tumor in …

Background: Malignant brain tumor is a highly challenging disease for diagnosis, treatment,
and management. Cytotoxicity, distribution and the ability to cross blood brain barrier are …

Malignant brain tumors are difficult to manage clinically and are associated with high rates of
morbidity and mortality. Late diagnosis and the limitations of conventional therapies that may …

Glioma is the most common type of Central Nervous System (CNS) neoplasia and it arises
from glial cells. As glial cells are formed by different types of cells, glioma can be classified …