RETRACTED ARTICLE: Inhibition of autophagic flux differently modulates cannabidiol-induced death in 2D and 3D glioblastoma cell cultures
Radiotherapy combined with chemotherapy is the major treatment modality for human
glioblastoma multiforme (GBM). GBMs eventually relapse after treatment and the average …
glioblastoma multiforme (GBM). GBMs eventually relapse after treatment and the average …
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
T Huang, T Xu, Y Wang, Y Zhou, D Yu, Z Wang, L He… - Autophagy, 2021 - Taylor & Francis
Glioma is the most common primary malignant brain tumor with poor survival and limited
therapeutic options. The non-psychoactive phytocannabinoid cannabidiol (CBD) has been …
therapeutic options. The non-psychoactive phytocannabinoid cannabidiol (CBD) has been …
[HTML][HTML] Inhibition of ATM kinase upregulates levels of cell death induced by cannabidiol and γ-irradiation in human glioblastoma cells
Despite advances in glioblastoma (GBM) therapy, prognosis of the disease remains poor
with a low survival rate. Cannabidiol (CBD) can induce cell death and enhance …
with a low survival rate. Cannabidiol (CBD) can induce cell death and enhance …
[HTML][HTML] Regulation of human glioblastoma cell death by combined treatment of cannabidiol, γ-radiation and small molecule inhibitors of cell signaling pathways
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The
challenging problem in cancer treatment is to find a way to upregulate radiosensitivity of …
challenging problem in cancer treatment is to find a way to upregulate radiosensitivity of …
Cannabidiol stimulates A ml‐1a‐dependent glial differentiation and inhibits glioma stem‐like cells proliferation by inducing autophagy in a TRPV 2‐dependent …
M Nabissi, MB Morelli, C Amantini… - … journal of cancer, 2015 - Wiley Online Library
Glioma stem‐like cells (GSCs) correspond to a tumor cell subpopulation, involved in
glioblastoma multiforme (GBM) tumor initiation and acquired chemoresistance. Currently …
glioblastoma multiforme (GBM) tumor initiation and acquired chemoresistance. Currently …
Inhalant cannabidiol inhibits glioblastoma progression through regulation of tumor microenvironment
Introduction: Glioblastoma (GBM) is the most common invasive brain tumor composed of
diverse cell types with poor prognosis. The highly complex tumor microenvironment (TME) …
diverse cell types with poor prognosis. The highly complex tumor microenvironment (TME) …
The Combination of Cannabidiol and Δ9-Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model
KA Scott, AG Dalgleish, WM Liu - Molecular cancer therapeutics, 2014 - AACR
High-grade glioma is one of the most aggressive cancers in adult humans and long-term
survival rates are very low as standard treatments for glioma remain largely unsuccessful …
survival rates are very low as standard treatments for glioma remain largely unsuccessful …
Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon …
X Sun, L Zhou, Y Wang, G Deng, X Cao, B Ke… - Journal of …, 2023 - Elsevier
Colorectal tumors often create an immunosuppressive microenvironment that prevents them
from responding to immunotherapy. Cannabidiol (CBD) is a non-psychoactive natural active …
from responding to immunotherapy. Cannabidiol (CBD) is a non-psychoactive natural active …
A combined preclinical therapy of cannabinoids and temozolomide against glioma
S Torres, M Lorente, F Rodríguez-Fornés… - Molecular cancer …, 2011 - AACR
Glioblastoma multiforme (GBM) is highly resistant to current anticancer treatments, which
makes it crucial to find new therapeutic strategies aimed at improving the poor prognosis of …
makes it crucial to find new therapeutic strategies aimed at improving the poor prognosis of …
Cannabidiol inhibits RAD51 and sensitizes glioblastoma to temozolomide in multiple orthotopic tumor models
L Soroceanu, E Singer, P Dighe… - Neuro-Oncology …, 2022 - academic.oup.com
Background Cannabidiol (CBD), a nonpsychoactive cannabinoid with a low toxicity profile,
has been shown to produce antitumor activity across cancers in part through selective …
has been shown to produce antitumor activity across cancers in part through selective …