Pregabalin overdose with benign outcome

HA Spiller, R Bratcher, JRK Griffith - Clinical Toxicology, 2008 - Taylor & Francis
Discussion Pregabalin is a newer antiepileptic drug developed for epilepsy, neuropathic
pain, and anxiety disorder (Citation 3). A review of Medline up to January 2008 revealed a …

Pregabalin and paradoxical reaction of seizures in a large overdose

GW Slocum, RF Schult, RM Gorodetsky… - Toxicology …, 2018 - Taylor & Francis
We report the case of a 54-year-old female with intentional pregabalin 3825 mg ingestion
that resulted in a rare adverse effect of a witnessed seizure with confirmatory serum …

Pregabalin poisoning: Evaluation of dose‐toxicity relationship

SJ Rietjens, MA Sikma, CC Hunault… - British journal of …, 2022 - Wiley Online Library
Context Pregabalin poisoning is mostly benign, although coma and convulsions
occasionally occur. Aim To determine the dose‐toxicity relationship of pregabalin. Methods …

Misuse of pregabalin: Case series and literature review

NE Suardi, M Preve, M Godio, E Bolla… - European …, 2016 - cambridge.org
IntroductionPregabalin is widely used in neurology, psychiatry and primary healthcare, and
recently in literature different studies explain the possible misuse [1, 2]. Pregabalin has …

Pregabalin poisoning and rising recreational use: a retrospective observational series

KZ Isoardi, G Polkinghorne, K Harris… - British journal of …, 2020 - Wiley Online Library
Aims With rising use worldwide, pregabalin is increasingly implicated in poisoning deaths.
We aimed to investigate the clinical effects and complications of pregabalin poisoning …

Significant pregabalin toxicity managed with supportive care alone

DM Wood, DJ Berry, G Glover, J Eastwood… - Journal of medical …, 2010 - Springer
There are two previously reported cases describing the management of pregabalin self-
poisoning and one further case of management of therapeutic pregabalin accumulation. The …

[PDF][PDF] Pregabalin dependence: a case report

P Bağımlılığı, G Oğuz, FM Güven, S Batmaz - J. Depend, 2015 - academia.edu
Pregabalin is a new generation antiepileptic drug that exerts its effects by decreasing the
release of neurotransmitters, such as glutamate, noradrenaline, and substance P …

Pregabalin dependence: a case report

A Halaby, S Abou Kassm, WJ Naja - Current drug safety, 2015 - pubmed.ncbi.nlm.nih.gov
Introduction Pregabalin is a gamma-aminobutyric acid (GABA) analogue approved for the
treatment of neuropathic pain, partial seizure and generalized anxiety disorder. As a GABA …

A case of pregabalin intoxication.

C Miljevic, C Crnobaric, S Nikolic… - Psychiatrike …, 2012 - europepmc.org
Pregabalin, or S-(+)-3-isobutylgaba, is a lipophilic analogue of GABA. Although pregabalin
is structurally related to GABA, it is inactive at GABA receptors and does not appear to mimic …

Nasal pregabalin overdose and myclonus: A new way of misuse

HM Ozturk, G Morkavuk - Psychiatry and Clinical …, 2019 - Taylor & Francis
Pregabalin reduces central neuronal excitability and has gamma-aminobutyric acid-mimetic
features, which was demonstrated in rats. Pregabalin is indicated for the treatment of …