[HTML][HTML] Aberrantly elevated Bmi1 promotes cervical cancer tumorigenicity and tumor sphere formation via enhanced transcriptional regulation of Sox2 genes

R Xu, L Chen, WT Yang - Oncology Reports, 2019 - spandidos-publications.com
The exact molecular mechanisms underlying cervical tumorigenesis are poorly understood.
Polycomb complex protein Bmi1 (Bmi1) is involved in the malignant transformation and …

Overexpression of Bmi-1 in uterine cervical cancer: correlation with clinicopathology and prognosis

X Zhang, CX Wang, C Zhu, J Zhang, S Kan… - International Journal of …, 2010 - ijgc.bmj.com
Introduction: B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) is a
member of polycomb group, which participates in axial patterning, hematopoiesis, cell cycle …

Overexpression of polycomb protein BMI-1 in human specimens of breast, ovarian, endometrial and cervical cancer

A Honig, C Weidler, S Häusler… - Anticancer …, 2010 - ar.iiarjournals.org
Introduction: The polycomb group (PcG) proteins form chromatin-modifying complexes that
are commonly deregulated in cancer. The PcG protein BMI-I is overexpressed by various …

Overexpression of BMI‐1 is associated with poor prognosis in cervical cancer

YQ Tong, B Liu, HY Zheng, YJ He… - Asia‐Pacific Journal …, 2012 - Wiley Online Library
Aim It has been reported that BMI‐1, a gene transcription promoter overexpressed in various
human cancers, is associated with poor survival. We investigated whether BMI‐1 is a marker …

[HTML][HTML] Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival

MK Kang, RH Kim, SJ Kim, FK Yip, KH Shin… - British Journal of …, 2007 - nature.com
Bmi-1 is a polycomb group protein that was identified as c-myc cooperating oncogene in
murine lymphomagenesis. The current study was undertaken to determine the role of Bmi-1 …

Expression of bmi-1 protein in cervical, breast and ovarian cancer

MM Gavrilescu, AM Todosi, MG ANITEI… - The Medical-Surgical …, 2012 - revmedchir.ro
B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) is a member of
polycomb group, which participates in axial patterning, hematopoiesis, cell cycle regulation …

[HTML][HTML] BMI‑1, a promising therapeutic target for human cancer

MC Wang, CL Li, J Cui, M Jiao, T Wu… - Oncology …, 2015 - spandidos-publications.com
BMI‑1 oncogene is a member of the polycomb‑group gene family and a transcriptional
repressor. Overexpression of BMI‑1 has been identified in various human cancer tissues …

[HTML][HTML] Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain

AK Yadav, AA Sahasrabuddhe, M Dimri, PV Bommi… - Molecular cancer, 2010 - Springer
Abstract Background The polycomb group (PcG) protein BMI1 is an important regulator of
development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell …

Bmi‐1 is critical for the proliferation and invasiveness of gastric carcinoma cells

W Li, Y Li, Y Tan, K Ma, J Cui - Journal of gastroenterology and …, 2010 - Wiley Online Library
Abstract Background and Aim: Bmi‐1 is a transcriptional repressor belonging to the
Polycomb group and is associated with the cell proliferation and carcinogenesis of a variety …

Polycomb protein BMI-1 as a potential therapeutic target in mucinous ovarian cancer

S Abobaker, H Kulbe, ET Taube… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Mucinous ovarian carcinoma (mOC) is a rare subtype with distinct clinical
characteristics and biological behavior that differentiate them from other epithelial ovarian …