The main principle of bone tissue engineering strategy is to use an osteoconductive porous
scaffold in combination with osteoinductive molecules or osteogenic cells. The requirements …

Nanostructured hydroxyapatite (HAp) has been applied widely as a scaffold material for
bone tissue engineering for its good osteoinduction and biodegradability. However, the …

Porous hydroxyapatite (HA) scaffolds are often used as bone repair materials, owing to their
good biocompatibility, osteoconductivity and low cost. Vascularization and osteoinductivity …

In this study, a nanostructured scaffold was designed for bone repair using hydroxyapatite
(HA) and gelatin (GEL) as its main components. Nanopowders of HA were synthesized, and …

It is well-accepted that most osteogenic differentiation processes do need growth factors
assistance to improve efficiency. As a material cue, hydroxyapatite (HAp) can promote …

The aim of this study was to develop chitosan composite scaffolds with high strength and
controlled pore structures by homogenously dispersed nano-sized hydroxyapatite (nano …

Vascularized bone grafts were constructed by implanting hydroxyapatite (HA) scaffolds with
complementary macro-pore structures into the dorsal muscle of dogs. The relationship …

In this work, a new methodology is reported for developing hydroxyapatite (HA) scaffolds
using an organic sacrifice template. The novelty of work consists of possibility of obtaining …

Current bioceramic scaffolds for critical-size bone defects are still facing various challenges
such as the poor capability of self-resorption, vascularization and osteogenesis. Herein, a …

Hierarchical porosity, which includes micropores and macropores in scaffolds, contributes to
important multiple biological functions for tissue regeneration. This paper introduces a two …