Nano-hydroxyapatite composite scaffolds loaded with bioactive factors and drugs for bone tissue engineering

X Mo, D Zhang, K Liu, X Zhao, X Li… - International Journal of …, 2023 - mdpi.com
Nano-hydroxyapatite (n-HAp) is similar to human bone mineral in structure and biochemistry
and is, therefore, widely used as bone biomaterial and a drug carrier. Further, n-HAp …

[HTML][HTML] Multiscale porous scaffolds constructed of carbonate apatite honeycomb granules for bone regeneration

K Hayashi, A Tsuchiya, M Shimabukuro, K Ishikawa - Materials & Design, 2022 - Elsevier
The use of scaffolds with pores ranging from macroscale to nanoscale (ie, multiscale pores),
is an effective strategy to achieve favorable bone regeneration. Here, we report the …

Alginate/nanohydroxyapatite scaffolds with designed core/shell structures fabricated by 3D plotting and in situ mineralization for bone tissue engineering

Y Luo, A Lode, C Wu, J Chang… - ACS applied materials & …, 2015 - ACS Publications
Composite scaffolds, especially polymer/hydroxyapatite (HAP) composite scaffolds with
predesigned structures, are promising materials for bone tissue engineering. Various …

In-situ hardening hydroxyapatite-based scaffold for bone repair

Y Zhang, HHK Xu, S Takagi, LC Chow - Journal of Materials Science …, 2006 - Springer
Musculoskeletal conditions are becoming a major health concern because of an aging
population and sports-and traffic-related injuries. While sintered hydroxyapatite implants …

Bioactive and biocompatible macroporous scaffolds with tunable performances prepared based on 3D printing of the pre‐crosslinked sodium alginate/hydroxyapatite …

S Liu, Y Hu, J Zhang, S Bao, L Xian… - Macromolecular …, 2019 - Wiley Online Library
Bioactive and biocompatible porous scaffold materials with adjustable pore structures and
drug delivery capability are one of the key elements in bone tissue engineering. In this work …

In vivo evaluation of porous hydroxyapatite/chitosan–alginate composite scaffolds for bone tissue engineering

HH Jin, DH Kim, TW Kim, KK Shin, JS Jung… - International journal of …, 2012 - Elsevier
Porous hydroxyapatite (HAp)/chitosan–alginate composite scaffolds were prepared through
in situ co-precipitation and freeze-drying for bone tissue engineering. The composite …

The synergetic effect of nano-structures and silicon-substitution on the properties of hydroxyapatite scaffolds for bone regeneration

L Xia, N Zhang, X Wang, Y Zhou, L Mao, J Liu… - Journal of Materials …, 2016 - pubs.rsc.org
Control over the morphology and chemical composition of hydroxyapatite (HAp) bioceramic
scaffolds is of great importance for their applications. In the present study, Si-substituted HAp …

A porous hydroxyapatite scaffold for bone tissue engineering: Physico-mechanical and biological evaluations

G Tripathi, B Basu - Ceramics International, 2012 - Elsevier
Polymer sponge replication method was used in this study to prepare the macroporous
hydroxyapatite scaffolds with interconnected oval shaped pores of 100–300μm with pore …

In vitro cellular response to hydroxyapatite scaffolds with oriented pore architectures

Q Fu, MN Rahaman, BS Bal, RF Brown - Materials Science and …, 2009 - Elsevier
The objective of the present work was to evaluate the in vitro cellular response to
hydroxyapatite (HA) scaffolds with oriented pore architectures. Hydroxyapatite scaffolds with …

Application of low-pressure system to sustain in vivo bone formation in osteoblast/porous hydroxyapatite composite

J Dong, T Uemura, H Kojima, M Kikuchi… - Materials Science and …, 2001 - Elsevier
Recently, synthetic porous hydroxyapatite (HA) has attracted a great deal of attention as a
bone graft substitute in the field of tissue engineering. Combining with bone marrow-derived …