Silicon substituted hydroxyapatite/VEGF scaffolds stimulate bone regeneration in osteoporotic sheep

L Casarrubios, N Gómez-Cerezo, S Sánchez-Salcedo… - Acta biomaterialia, 2020 - Elsevier
Silicon-substituted hydroxyapatite (SiHA) macroporous scaffolds have been prepared by
robocasting. In order to optimize their bone regeneration properties, we have manufactured …

Enhanced osteogenesis through nano-structured surface design of macroporous hydroxyapatite bioceramic scaffolds via activation of ERK and p38 MAPK signaling …

L Xia, K Lin, X Jiang, Y Xu, M Zhang, J Chang… - Journal of Materials …, 2013 - pubs.rsc.org
The design of the three-dimensional (3D) porous structures and surface morphological/
topographies of implants is considered as a novel approach to enhance the bioactivity and …

Effects of macropore size in carbonate apatite honeycomb scaffolds on bone regeneration

K Hayashi, ML Munar, K Ishikawa - Materials Science and Engineering: C, 2020 - Elsevier
The pore architecture of scaffolds is a critical factor for angiogenesis and bone regeneration.
Although the effects of scaffold macropore size have been investigated, most scaffolds …

[HTML][HTML] Preparation and characterization of homogeneous hydroxyapatite/chitosan composite scaffolds via in-situ hydration

H Li, CR Zhou, MY Zhu, JH Tian, JH Rong - Journal of Biomaterials and …, 2010 - scirp.org
Hydroxyapatite (HAP)/Chitosan (CS) composite is a biocompatible and bioactive material for
tissue engineering. A novel homogeneous HAP/CS composite scaffold was developed via …

Fabrication and in vivo evaluation of an osteoblast‐conditioned nano‐hydroxyapatite/gelatin composite scaffold for bone tissue regeneration

A Samadikuchaksaraei… - … Research Part A, 2016 - Wiley Online Library
In this study, the effects of osteoblast‐conditioning on mechanical behavior, biocompatibility,
biodegradation and osteoinductive properties of a nano‐hydroxyapatite/gelatin (HA/GEL) …

The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity

JR Woodard, AJ Hilldore, SK Lan, CJ Park, AW Morgan… - Biomaterials, 2007 - Elsevier
The relative osteoconductivity and the change in the mechanical properties of
hydroxyapatite (HA) scaffolds with multi-scale porosity were compared to scaffolds with a …

[PDF][PDF] Nanometre scale hydroxyapatite ceramics for bone tissue engineering

GEJ Poinern, RK Brundavanam… - American Journal of …, 2013 - researchgate.net
The consequences of bone traumatisation, loss or damage, resulting from injury or disease
can dramatically reduce the quality of life for a patient at a significant socioeconomic cost …

In situ fabrication of nano-hydroxyapatite in a macroporous chitosan scaffold for tissue engineering

JD Chen, Y Wang, X Chen - Journal of Biomaterials Science …, 2009 - Taylor & Francis
A chitosan (CS)/hydroxyapatite (HAP) nanohybrid scaffold with high porosity and
homogeneous nanostructure was fabricated through a bionic treatment combined with …

[HTML][HTML] Macropore regulation of hydroxyapatite osteoinduction via microfluidic pathway

F Shi, X Fang, T Zhou, X Huang, K Duan… - International Journal of …, 2022 - mdpi.com
Macroporous characteristics have been shown to play a key role in the osteoinductivity of
hydroxyapatite ceramics, but the physics underlying the new bone formation and distribution …

Hybrid nanostructured hydroxyapatite–chitosan composite scaffold: Bioinspired fabrication, mechanical properties and biological properties

YP Guo, JJ Guan, J Yang, Y Wang… - Journal of Materials …, 2015 - pubs.rsc.org
The fabrication of bone scaffolds with interconnected porous structure, adequate mechanical
properties, excellent biocompatibility and osteoinductivity presents a great challenge …