Presently, commercially available porous bone substitutes are manufactured by the
sacrificial template method, direct foaming method, and polymer replication method (PRM) …

Bone tissue engineering holds great promise for the regeneration of damaged or severe
bone defects. However, several challenges hinder its translation into clinical practice. To …

We developed fully opened interconnected porous calcium hydroxyapatite ceramics having
two different pore sizes. One has pores with an average size of 150 μm in diameter, an …

The ability to encapsulate cells in three-dimensional (3D) protein-based hydrogels is
potentially of benefit for tissue engineering and regenerative medicine. However, as a result …

The repair of large maxillofacial bony defects using regular scaffolds is restricted by the
osteogenic effect. It was postulated that a novel porous hydroxyapatite (HA) scaffolds with a …

Additive manufacturing enables the realization of the macro-and microarchitecture of bone
substitutes. The macroarchitecture is determined by the bone defect and its shape makes …

The scaffold chemical composition and pore architecture are critical for successful bone
regeneration. Although the effects of chemical composition, micron-scale pores, and …

Porous hydroxyapatite (HA) scaffolds have been intensively studied and developed for bone
tissue engineering, but their mechanical properties remain to be improved. The aim of this …

Porous bone tissue engineering scaffolds were fabricated using both nano hydroxyapatite
(nano HA) powder (20 nm average particle size) and micro HA powder (10 μm average …

Three different porous scaffolds were tested. The first two were prepared by sintering bovine
bone. The third scaffold was prepared using three-dimensional gel-lamination, a new rapid …