Overnutrition and a sedentary lifestyle have resulted in the expansion of human obesity and
associated metabolic complications. Nonalcoholic fatty liver disease has become the most …

Fatty liver disease, characterized by excessive inflammation and lipid deposition, is
becoming one of the most prevalent liver metabolic diseases worldwide owing to the …

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide, and
a major cause of liver cirrhosis and hepatocellular carcinoma. NAFLD is intimately linked …

The liver is the site of first pass metabolism, detoxifying and metabolizing blood arriving from
the hepatic portal vein and hepatic artery. It is made up of multiple cell types, including …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries that could lead to serious health problems including liver failure …

Obesity is causally linked to a chronic state of “low-grade” inflammation in adipose tissue.
Prolonged, unremitting inflammation in this tissue has a direct impact on insulin-sensitive …

Non‐alcoholic fatty liver disease (NAFLD), recently also defined as metabolic dysfunction‐
associated fatty liver disease (MAFLD), is a major health problem, as it affects∼ 25% of the …

Hepatic macrophages are a remarkably heterogeneous population consisting of self-
renewing tissue-resident phagocytes, termed Kupffer cells (KCs), and recruited …

Mechanisms for non-alcoholic steatohepatitis (NASH) development are under investigation
in an era of increased prevalence of obesity and metabolic syndrome. Previous findings …

Obesity is increasingly being recognized as a risk factor for a number of benign and
malignant gastrointestinal conditions. However, literature on the underlying …