An increase in the extracellular concentration of dopamine in the nucleus accumbens (NAc)
is believed to be one of the main mechanisms involved in the rewarding and motor …

Adenosine, by acting on adenosine A1 and A2A receptors, exerts opposite modulatory roles
on striatal extracellular levels of glutamate and dopamine, with activation of A1 inhibiting …

Previous studies have demonstrated opposing roles for adenosine A1 and A2A receptors in
the modulation of extracellular levels of glutamate and dopamine in the striatum. In the …

The effects of caffeine on extracellular dopamine and acetylcholine have been studied in
freely moving rats implanted with concentric microdialysis probes in the nucleus accumbens …

Caffeine is the most widely used psychoactive substance and has been considered
occasionally as a drug of abuse. The present paper reviews available data on caffeine …

Background The psychostimulant properties of caffeine are reviewed and compared with
those of prototypical psychostimulants able to cause substance use disorders (SUD) …

Caffeine, the most widely consumed of all psychostimulant drugs, exerts its action by
antagonizing adenosine receptors. To study the arousing properties of caffeine, we injected …

Caffeine is the most widely consumed psychostimulant substance, being self-administered
throughout a wide range of conditions and present in numerous dietary products. Due to its …

The effects of carbamazepine and caffeine on adenosine receptor subtypes were
determined using in vivo microdialysis in an attempt to elucidate their different psychotropic …

Dopamine has been proposed to mediate some of the behavioral effects of caffeine. This
review discusses cellular mechanisms of action that could explain the role of dopamine in …