[HTML][HTML] Preclinical evidence supporting the clinical development of central pattern generator-modulating therapies for chronic spinal cord-injured patients

PA Guertin - Frontiers in human neuroscience, 2014 - frontiersin.org
Ambulation or walking is one of the main gaits of locomotion. In terrestrial animals, it may be
defined as a series of rhythmic and bilaterally coordinated movement of the limbs which …

Key central pattern generators of the spinal cord

PA Guertin, I Steuer - Journal of neuroscience research, 2009 - Wiley Online Library
In the central nervous system (CNS), central pattern generators (CPGs) are generally
considered as specialized networks that can produce oscillatory motor output in the absence …

The human central pattern generator for locomotion: does it exist and contribute to walking?

K Minassian, US Hofstoetter, F Dzeladini… - The …, 2017 - journals.sagepub.com
The ability of dedicated spinal circuits, referred to as central pattern generators (CPGs), to
produce the basic rhythm and neural activation patterns underlying locomotion can be …

Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences

I Steuer, PA Guertin - Reviews in the Neurosciences, 2019 - degruyter.com
Central pattern generators (CPGs) are generally defined as networks of neurons capable of
enabling the production of central commands, specifically controlling stereotyped, rhythmic …

Tonic and rhythmic spinal activity underlying locomotion

YP Ivanenko, VS Gurfinkel… - Current …, 2017 - ingentaconnect.com
In recent years, many researches put significant efforts into understanding and assessing
the functional state of the spinal locomotor circuits in humans. Various techniques have …

Neuromodulation of spinal locomotor networks in rodents

M Diaz-Ríos, PA Guertin… - Current pharmaceutical …, 2017 - ingentaconnect.com
Background: The basic motor patterns driving rhythmic limb movements during walking are
generated by networks of neurons called central pattern generators (CPGs). Within motor …

[HTML][HTML] Tapping into rhythm generation circuitry in humans during simulated weightlessness conditions

IA Solopova, VA Selionov, F Sylos-Labini… - Frontiers in systems …, 2015 - frontiersin.org
An ability to produce rhythmic activity is ubiquitous for locomotor pattern generation and
modulation. The role that the rhythmogenesis capacity of the spinal cord plays in injured …

[HTML][HTML] Central pattern generators and the control of rhythmic movements

E Marder, D Bucher - Current biology, 2001 - cell.com
Central pattern generators are neuronal circuits that when activated can produce rhythmic
motor patterns such as walking, breathing, flying, and swimming in the absence of sensory …

Central pattern generation of locomotion: a review of the evidence

M MacKay-Lyons - Physical therapy, 2002 - academic.oup.com
Neural networks in the spinal cord, referred to as “central pattern generators”(CPGs), are
capable of producing rhythmic movements, such as swimming, walking, and hopping, even …

Do pacemakers drive the central pattern generator for locomotion in mammals?

F Brocard, S Tazerart, L Vinay - The Neuroscientist, 2010 - journals.sagepub.com
Locomotor disorders profoundly impact quality of life of patients with spinal cord injury.
Understanding the neuronal networks responsible for locomotion remains a major challenge …