Malignancies of thymus-derived (T) lymphocytes can be divided into two major groups:
diseases of T cells expressing immature T cell markers (T-ALL, T cell lymphoblastic …

Untreated T cell malignancies (82) and T leukaemic cell lines (13) have been analysed by
fluorescence microscopy and flow cytometry (FACS) using a series of monoclonal …

This article discusses the ontogeny of human T cells along with the relationship of normal T-
cell maturation to the development of various malignant T-cell syndromes. The impact of …

The present study sought to delineate the phenotypic heterogeneity of the human T‐cell
malignancies. Twenty T‐cell neoplasms were investigated for reactivity with the OKT …

ABSTRACT T-cells comprise many subtypes of specified lymphocytes, and their
differentiation and function take place in different tissues. This cellular diversity is also …

The expression profiles of eight cell lines derived from T-cell malignancies were compared
to CD4-positive T-cells using cDNA microarray technology. Unsupervised hierarchical …

Differentiation of immunocompetent lymphocytes from hematopeietic precursors
(presumably via multistep branching pathways) results in the emergence of several mature …

Cell surface antigenic changes occur during the stages of T-cell ontogeny in several animal
model systems. In the present study, multiple monoclonal antibodies were developed to …

Twenty-three T-cell neoplasms were investigated for their reactivity with the OKT monoclonal
antibodies and expression of certain cytochemical markers. Fourteen neoplasms with …

Tumor cells from eight adult patients with T-cell chronic malignancies were investigated with
a series of monoclonal antibodies recognizing T-cell differentiation antigens. This series …