Bone and the immune system

MN Weitzmann - Bone Toxicology, 2017 - Springer
The mechanisms that control physiological and pathological bone mass and turnover have
been extensively investigated over the past several decades. One surprising discovery that …

Multifunctional titanium surfaces for orthopedic implants: Antimicrobial activity and enhanced osseointegration

F Ghilini, N Fagali, DE Pissinis, G Benítez… - ACS Applied Bio …, 2021 - ACS Publications
The use of implants in orthopedics and dental practice is a widespread surgical procedure to
treat diverse diseases. However, peri-implantitis due to infections and/or poor …

Foreign body reaction to biomaterials: on mechanisms for buildup and breakdown of osseointegration

R Trindade, T Albrektsson, P Tengvall… - … implant dentistry and …, 2016 - Wiley Online Library
Background The last few decades have seen a progressive shift in paradigm, replacing the
notion of body implants as inert biomaterials for that of immune‐modulating interactions with …

The effect of ordered and partially ordered surface topography on bone cell responses: a review

N Gui, W Xu, DE Myers, R Shukla, HP Tang… - Biomaterials …, 2018 - pubs.rsc.org
Implant surfaces play important roles in regulating protein adsorption and determining
subsequent cell responses, including cell attachment, proliferation, migration and …

Controlling osteoblast morphology and proliferation via surface micro-topographies of implant biomaterials

K Rabel, RJ Kohal, T Steinberg, P Tomakidi… - Scientific reports, 2020 - nature.com
Current research on surface modifications has yielded advanced implant biomaterials.
Various implant surface modifications have been shown to be promising in improving bone …

Preventing peri-implantitis: the quest for a next generation of titanium dental implants

J Hasan, R Bright, A Hayles, D Palms… - ACS Biomaterials …, 2022 - ACS Publications
Titanium and its alloys are frequently the biomaterial of choice for dental implant
applications. Although titanium dental implants have been utilized for decades, there are yet …

Role of the osteoclast at the bone-implant interface

C Minkin, VC Marinho - Advances in dental research, 1999 - journals.sagepub.com
A thorough understanding of the processes of healing, repair, and remodeling of bone is
critical for the establishment and maintenance of osseointegration of dental implants. In this …

Titanium coatings and surface modifications: toward clinically useful bioactive implants

A Civantos, E Martínez-Campos, V Ramos… - ACS Biomaterials …, 2017 - ACS Publications
Titanium (Ti) is broadly used for clinical purposes in various medical fields related to bone
repair because of its favorable mechanical properties and its ability to osseointegrate in host …

[HTML][HTML] Osteoimmunology: interactions of the immune and skeletal systems

J Rho, M Takami, Y Choi - Molecules and cells, 2004 - Elsevier
Bone is a dynamic tissue that provides mechanical support, physical protection, and enables
movement. Bone also serves as a storage site for minerals and is where blood cells are …

Titanium oral implants: surface characteristics, interface biology and clinical outcome

A Palmquist, OM Omar, M Esposito… - Journal of the …, 2010 - royalsocietypublishing.org
Bone-anchored titanium implants have revolutionized oral healthcare. Surface properties of
oral titanium implants play decisive roles for molecular interactions, cellular response and …