Evaluation of filtration leucocytapheresis for use in the treatment of patients with rheumatoid arthritis

Y Ueki, S Yamasaki, Y Kanamoto, T Kawazu… - …, 2000 - academic.oup.com
Objectives. To evaluate the efficacy of filtration leucocytapheresis (LCP) for rheumatoid
arthritis (RA). Methods. LCP was carried out three times, with 1 week separating each …

Filtration leukocytapheresis therapy in rheumatoid arthritis: a randomized, double‐blind, placebo‐controlled trial

T Hidaka, K Suzuki, Y Matsuki… - … : Official Journal of …, 1999 - Wiley Online Library
Objective To determine the efficacy and safety of filtration leukocytapheresis (LCP) for the
treatment of rheumatoid arthritis (RA). Methods Twenty‐five patients with drug‐resistant RA …

The mechanism of the efficiency of leukocytapheresis on rheumatoid arthritis

T Hidaka, K Suzuki - Therapeutic Apheresis, 1997 - Wiley Online Library
This study was designed to determine the efficacy of filtration leukocytapheresis (LCAP) in
the treatment of rheumatoid arthritis (RA) and the mechanism of its efficacy. Three filtration …

Dynamic changes in cytokine levels in serum and synovial fluid following filtration leukocytapheresis therapy in patients with rheumatoid arthritis

T Hidaka, K Suzuki, M Kawakami… - Journal of Clinical …, 2001 - Wiley Online Library
We attempted to determine whether various cytokine levels in the serum and synovial fluid
(SF) of rheumatoid arthritis (RA) patients are influenced by the performance of filtration …

Filtration leukocytapheresis therapy in the treatment of rheumatoid arthritis patients resistant to or failed with methotrexate

K Kempe, H Tsuda, K Yang, K Yamaji… - Therapeutic …, 2004 - Wiley Online Library
Filtration leukocytapheresis (LCP) is a treatment for abnormal autoimmune states, which
removes responsible leukocytes from the peripheral blood. To examine the efficacy of LCP …

Changes in CD4+ T lymphocyte subsets in circulating blood and synovial fluid following filtration leukocytapheresis therapy in patients with rheumatoid arthritis

T Hidaka, K Suzuki, Y Matsuki… - Therapeutic …, 1999 - Wiley Online Library
The purpose of this study is to determine the changes in CD4+ T lymphocyte subsets in the
circulating blood and synovial fluid following filtration leukocytapheresis (LCP) therapy for …

Enhanced effect of high-dose leukocytapheresis using a large filter in rheumatoid arthritis

K Eguchi, K Saito, M Kondo, T Hidaka, Y Ueki… - Modern …, 2007 - Taylor & Francis
To evaluate the efficacy of high-dose leukocytapheresis (LCAP) using a large filter in
patients with refractory rheumatoid arthritis (RA), we conducted a multicenter …

Efficacy of filtration leukocytapheresis on rheumatoid arthritis with vasculitis

T Hidaka, K Suzuki - Therapeutic Apheresis, 1997 - Wiley Online Library
The present study was designed to determine the efficacy of filtration leukocytapheresis
(LCAP) in the treatment of rheumatoid arthritis (RA) with vasculitis. Nine RA patients with …

Twenty-four-week follow-up examination of a leukocytapheresis therapy in rheumatoid arthritis

Y Izumi, M Tominaga, N Iwanaga, M Huang… - Modern …, 2006 - academic.oup.com
Several clinical trials have demonstrated that leukocytapheresis (LCAP) is a safe and
effective therapy for patients with refractory rheumatoid arthritis (RA). However, most of those …

Evaluation of a filtration lymphocytapheresis (LCP) device for use in the treatment of patients with rheumatoid arthritis

T Kondoh, Y Hidaka, H Katoh, N Inoue… - Artificial …, 1991 - Wiley Online Library
A practical on–line lymphocytapheresis (LCP) system using a leukapheresis filter
(Cellsorba, Asahi Medical Co.) was evaluated in six patients with refractory rheumatoid …