Hypoxic-ischemic encephalopathy (HIE) is a severe central nervous system injury in
neonates secondary to perinatal asphyxia. It may cause devastating lifelong neurocognitive …

Importance Hypothermia initiated at less than 6 hours after birth reduces death or disability
for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. To our …

Hypoxic ischemic encephalopathy (HIE) is a serious neurological complication that may
develop in asphyxiated infants. Severity of encephalopathy may vary, and concurrent …

Background Despite therapeutic hypothermia (TH) and neonatal intensive care, 45–50% of
children affected by moderate‑to‑severe neonatal hypoxic‑ischemic encephalopathy (HIE) …

OBJECTIVE: To examine the predictive ability of stage of hypoxic-ischemic encephalopathy
(HIE) for death or moderate/severe disability at 18 months among neonates undergoing …

Acute postasphyxial encephalopathy around the time of birth remains a major cause of
death and disability. The possibility that hypothermia may be able to prevent or lessen …

Objective Hypoxic–ischemic encephalopathy (HIE) is a leading cause of morbidity and
mortality in neonates. Therapeutic hypothermia (TH) has improved outcomes and mortality …

Despite advances in obstetric care, hypoxic ischemic encephalopathy (HIE) remains a
significant disease burden. Using a national dataset, we determined the trends of HIE …

Context Clinicians use brain magnetic resonance imaging (MRI) to discuss
neurodevelopmental prognosis with parents of neonates with hypoxic-ischemic …

Therapeutic hypothermia is now standard of care for neonates with hypoxic-ischemic
encephalopathy (HIE) in high income countries (HIC). Conversely, compelling trial evidence …