CRP-like transcriptional regulator MrpC curbs c-di-GMP and 3′, 3′-cGAMP nucleotide levels during development in Myxococcus xanthus

S Kuzmich, P Blumenkamp, D Meier, D Szadkowski… - MBio, 2022 - Am Soc Microbiol
Myxococcus xanthus has a nutrient-regulated biphasic life cycle forming predatory swarms
in the presence of nutrients and spore-filled fruiting bodies in the absence of nutrients. The …

A novel “four-component” two-component signal transduction mechanism regulates developmental progression in Myxococcus xanthus

S Jagadeesan, P Mann, CW Schink, PI Higgs - Journal of Biological …, 2009 - ASBMB
Histidine-aspartate phosphorelays are employed by two-component signal transduction
family proteins to mediate responses to specific signals or stimuli in microorganisms and …

Analyses of mrp Genes during Myxococcus xanthus Development

H Sun, W Shi - Journal of Bacteriology, 2001 - Am Soc Microbiol
Myxococcus xanthus is a gram-negative soil bacterium that undergoes development under
starvation conditions. Our previous study identified a new genetic locus, mrp, which is …

Crp of Streptomyces coelicolor is the third transcription factor of the large CRP-FNR superfamily able to bind cAMP

A Derouaux, D Dehareng, E Lecocq, S Halici… - Biochemical and …, 2004 - Elsevier
The chromosomal inactivation of the unique transcription factor of Streptomyces coelicolor
that displays a cyclic-nucleotide-binding domain, CrpSco, led to a germination-defective …

A novel bacterial signalling system with a combination of a Ser/Thr kinase cascade and a His/Asp two‐component system

R Lux, W Shi - Molecular microbiology, 2005 - Wiley Online Library
Prokaryotes and eukaryotes have long been thought to use very different types of kinases
(the His kinases of the 'bacterial'two‐component systems versus the 'eukaryotic'Ser/Thr/Tyr …

Dual Regulation with Ser/Thr Kinase Cascade and a His/Asp TCS in Myxococcus xanthus

S Inouye, H Nariya - Bacterial signal transduction: networks and drug …, 2008 - Springer
Fruiting body development of Myxococcus xanthus is propelled by temporal gene
expression directed via stage-specific intercellular signaling pathways. M. xanthus exhibits …

Combinatorial Regulation of the dev Operon by MrpC2 and FruA during Myxococcus xanthus Development

A Campbell, P Viswanathan, T Barrett, B Son… - Journal of …, 2015 - Am Soc Microbiol
Proper expression of the dev operon is important for normal development of Myxococcus
xanthus. When starved, these bacteria coordinate their gliding movements to build mounds …

A CRISPR with roles in Myxococcus xanthus development and exopolysaccharide production

RA Wallace, WP Black, X Yang, Z Yang - Journal of bacteriology, 2014 - Am Soc Microbiol
The Gram-negative soil bacterium Myxococcus xanthus utilizes its social (S) gliding motility
to move on surfaces during its vegetative and developmental cycles. It is known that S …

Mutation of rpoB Shifts the Nutrient Threshold Triggering Myxococcus Multicellular Development

SA Eisner, GJ Velicer, YTN Yu - Frontiers in Microbiology, 2022 - frontiersin.org
The ability to perceive and respond to environmental change is essential to all organisms. In
response to nutrient depletion, cells of the soil-dwelling δ-proteobacterium Myxococcus …

Combinatorial Regulation by MrpC2 and FruA Involves Three Sites in the fmgE Promoter Region during Myxococcus xanthus Development

B Son, Y Liu, L Kroos - Journal of bacteriology, 2011 - Am Soc Microbiol
Starvation causes cells in a dense population of Myxococcus xanthus to change their gliding
movements and construct mounds. Short-range C-signaling between rod-shaped cells …