Levothyroxine for the treatment of subclinical hypothyroidism and cardiovascular disease

LY Sue, AM Leung - Frontiers in endocrinology, 2020 - frontiersin.org
Subclinical hypothyroidism is a biochemical condition defined by elevated serum thyroid-
stimulating hormone levels in the setting of normal levels of the peripheral thyroid hormones …

Cardiovascular events in thyroid disease: a population based, prospective study

M Schultz, C Kistorp, I Raymond… - Hormone and …, 2011 - thieme-connect.com
No consensus exists whether subclinical thyroid disease should be treated or just observed.
Untreated overt thyroid disease is associated with increased risk of cardiovascular disease …

Cardiac dysrhythmias and thyroid dysfunction-The hidden menace?

F Osman, MD Gammage, MC Sheppard… - The Journal of …, 2002 - academic.oup.com
Thyrotoxicosis is often perceived as a reversible disorder without long-term consequences,
perhaps because of the availability of effective treatments, but recent evidence suggests that …

Hypothyroidism and dyslipidemia: modern concepts and approaches

EN Pearce - Current cardiology reports, 2004 - Springer
Subclinical and overt hypothyroidism are relatively common disorders in the general
population. Thyroid hormone is known to play a role in regulating the synthesis, metabolism …

Risk factors for cardiovascular disease in women with subclinical hypothyroidism

R Luboshitzky, A Aviv, P Herer, L Lavie - Thyroid, 2002 - liebertpub.com
Overt hypothyroidism may result in accelerated atherosclerosis and coronary heart disease
(CHD) presumably because of the associated hypertension, hypercholesterolemia, and …

Effects of thyroid hormones on the heart

H Vargas-Uricoechea, A Bonelo-Perdomo… - Clínica e Investigación …, 2014 - Elsevier
Thyroid hormones have a significant impact on heart function, mediated by genomic and
non-genomic effects. Consequently, thyroid hormone deficiencies, as well as excesses, are …

Hypothyroidism and atherosclerotic heart disease: pathogenesis, medical management, and the role of coronary artery bypass surgery

C Becker - Endocrine reviews, 1985 - academic.oup.com
Overt Hypothyroidism is associated with a number of abnormalities in lipid metabolism
which may predispose patients to accelerated coronary artery disease. Despite a high …

Thyroid and lipid metabolism

E Pucci, L Chiovato, A Pinchera - International Journal of Obesity, 2000 - nature.com
Thyroid hormones influence all major metabolic pathways. Their most obvious and well-
known action is an increase in basal energy expenditure obtained acting on protein …

Recognition and management of cardiovascular disease related to thyroid dysfunction

PW Ladenson - The American journal of medicine, 1990 - Elsevier
Hypothyroidism and hyperthyroidism are both associated with clinically significant
cardiovascular derangements. In hypothyroidism, these include pericardial effusion, heart …

Thyroid hormone and cardiovascular disease

M Gomberg-Maitland, WH Frishman - American heart journal, 1998 - Elsevier
Thyroid hormone directly affects the heart and peripheral vascular system. The hormone can
increase myocardial inotropy and heart rate and dilate peripheral arteries to increase …