[HTML][HTML] The Synergistic Effects of Polysaccharides and Ginsenosides From American Ginseng (Panax quinquefolius L.) Ameliorating Cyclophosphamide-Induced …

R Zhou, D He, J Xie, Q Zhou, H Zeng, H Li… - Frontiers in …, 2021 - frontiersin.org
Cyclophosphamide (CTX), used in cancer chemotherapy, a high dose of which would cause
immunosuppressive effect and intestinal mucosa damage. American ginseng (Panax …

[HTML][HTML] Insight Into Polysaccharides From Panax ginseng CA Meyer in Improving Intestinal Inflammation: Modulating Intestinal Microbiota and Autophagy

D Wang, S Shao, Y Zhang, D Zhao… - Frontiers in …, 2021 - frontiersin.org
Polysaccharides from Panax ginseng CA Meyer (P. ginseng) are the main active component
of P. ginseng and exhibit significant intestinal anti-inflammatory activity. However, the …

Exopolysaccharides from Genistein-Stimulated Monascus purpureus Ameliorate Cyclophosphamide-Induced Intestinal Injury via PI3K/AKT-MAPKs/NF-κB Pathways …

L Xie, T Chen, X Qi, H Li, J Xie, L Wang… - Journal of Agricultural …, 2023 - ACS Publications
Exopolysaccharides from genistein-stimulated Monascus purpureus (G-EMP) exhibited
immunomodulatory potential in vitro, but whether it had immune-enhancing effects in vivo …

[HTML][HTML] Ginsenoside Rg1 alleviates acute ulcerative colitis by modulating gut microbiota and microbial tryptophan metabolism

H Cheng, J Liu, D Zhang, J Wang, Y Tan… - Frontiers in …, 2022 - frontiersin.org
Ulcerative colitis (UC) is a chronic and recurrent inflammatory disorder in the gastrointestinal
tract. Here, we examined the pharmacological effects of ginsenoside Rg1, a natural …

Ginger polysaccharides enhance intestinal immunity by modulating gut microbiota in cyclophosphamide-induced immunosuppressed mice

J Liu, J Wang, S Zhou, D Huang, G Qi… - International Journal of …, 2022 - Elsevier
In this study, the immunity-enhancing effect of ginger polysaccharides UGP1 and UGP2 on
CTX-induced immunosuppressed mice was evaluated. The results showed that ginger …

Systematic exploration of Astragalus membranaceus and Panax ginseng as immune regulators: Insights from the comparative biological and computational analysis

J Liu, SH Nile, G Xu, Y Wang, G Kai - Phytomedicine, 2021 - Elsevier
Background Immune system plays a decisive role for defending various pathogenic
microorganisms. Astragalus membranaceus (AM) and Panax ginseng (PG) are two tonic …

The dual roles of ginsenosides in improving the anti-tumor efficiency of cyclophosphamide in mammary carcinoma mice

H Zhu, YS He, J Ma, J Zhou, M Kong, CY Wu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Cyclophosphamide (CTX) is a first line chemotherapeutic
agent, but often limited for its unstable therapeutic effect and serious side effects …

Effects of Panax ginseng polysaccharides on the gut microbiota in mice with antibiotic-associated diarrhea

S Li, Y Qi, L Chen, D Qu, Z Li, K Gao, J Chen… - International journal of …, 2019 - Elsevier
Panax ginseng is a traditional medicinal plant used in most Asian countries to cure many
diseases. The benefits of ginseng are due to its primary active component, polysaccharides …

Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition

X Bai, R Fu, Z Duan, Y Liu, C Zhu, D Fan - Food & Function, 2021 - pubs.rsc.org
Ginsenoside Rh4, as a bioactive component obtained from Panax notoginseng, has
excellent pharmacological properties. However, its role in regulating gut microbiota and …

[HTML][HTML] Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in ApcMin/+ mice

G Huang, I Khan, X Li, L Chen, W Leong, LT Ho… - Scientific Reports, 2017 - nature.com
Studies showed that manipulation of gut microbiota (GM) composition through the treatment
of prebiotics could be a novel preventive measure against colorectal cancer (CRC) …