Potential of anti-inflammatory agents for treatment of atherosclerosis

DA Chistiakov, AA Melnichenko, AV Grechko… - … and molecular pathology, 2018 - Elsevier
Chronic inflammation is a central pathogenic mechanism of atherosclerosis induction and
progression. Vascular inflammation is associated with accelerated onset of late …

Role of inflammation in the pathogenesis of atherosclerosis and therapeutic interventions

P Raggi, J Genest, JT Giles, KJ Rayner, G Dwivedi… - Atherosclerosis, 2018 - Elsevier
Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Anti-inflammatory therapeutics for the treatment of atherosclerosis

IF Charo, R Taub - Nature reviews Drug discovery, 2011 - nature.com
Atherosclerosis is the primary cause of heart disease and stroke and is thus the underlying
pathology of the leading causes of death in the western world. Although risk can be reduced …

Inflammation: a novel therapeutic target/direction in atherosclerosis

B Li, W Li, X Li, H Zhou - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …

Research progress on the relationship between atherosclerosis and inflammation

Y Zhu, X Xian, Z Wang, Y Bi, Q Chen, X Han, D Tang… - Biomolecules, 2018 - mdpi.com
Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture,
vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute …

Updating concepts on atherosclerotic inflammation: From pathophysiology to treatment

S Ministrini, F Carbone… - European Journal of …, 2021 - Wiley Online Library
Background Atherosclerosis is recognized as a systemic low‐grade inflammatory disease.
Furthermore, the dysregulation of the inflammatory response and its timely resolution is a …

[HTML][HTML] Inflammation in atherosclerosis

S Taleb - Archives of cardiovascular diseases, 2016 - Elsevier
Atherosclerosis is an inflammatory disease within the arterial wall that is responsible for
several important adverse vascular events, including coronary artery disease, myocardial …

Anti-inflammatory therapies for atherosclerosis

M Bäck, GK Hansson - Nature Reviews Cardiology, 2015 - nature.com
The view of atherosclerosis as an inflammatory disease has emerged from observations of
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …

Inflammation and atherosclerosis—revisited

S Pant, A Deshmukh, GS GuruMurthy… - Journal of …, 2014 - journals.sagepub.com
Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …

Anti-inflammatory therapy for atherosclerosis: focusing on cytokines

AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
Atherosclerosis is a well-known global health problem. Despite the high prevalence of the
disease, numerous aspects of pathogenesis remain unclear. Subsequently, there are still no …