Intestinal mucosal barrier function is the capacity of the intestine to provide adequate
containment of luminal microorganisms and molecules while preserving the ability to absorb …

Inflammatory bowel disease (IBD) is an idiopathic disease thought to be caused by a
dysregulated immune response to host intestinal microflora. The role of genetic factors is …

Over the past decade a major hypothesis has emerged for the etiopathogenesis of
inflammatory bowel disease (IBD). This hypothesis proposes that IBD represents a …

Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the
gastrointestinal tract, including Crohn's disease, ulcerative colitis and inflammatory bowel …

There are now many experimental models of inflammatory bowel disease (IBD), most of
which are due to induced mutations in mice that result in an impaired homeostasis with the …

Inflammatory bowel disease (IBD) is a group of idiopathic, chronic and relapsing
inflammatory conditions of the gastrointestinal tract. Familial and epidemiological studies …

Over the past 25 years, substantial advances have been made in our understanding of the
cellular and molecular pathways that are essential to maintain a state of health in the …

The primary functions of the gastrointestinal tract have traditionally been perceived to be
limited to the digestion and absorption of nutrients and electrolytes, and to water …

Inflammatory bowel disease (IBD) has long been known to arise from the interplay between
host and environmental factors. From this, a picture is currently emerging in which IBD is …

The human gut relies on several cellular and molecular mechanisms to allow for an intact
and dynamical intestinal barrier. Normally, only small amounts of luminal content pass the …