Inflammatory bowel diseases are the consequence of a dysregulated mucosal immune
system. The mucosal immune system consists of two arms, innate and adaptive immunity …

Monogenic causes of inflammatory bowel diseases (IBD) are increasingly being discovered.
To date, much attention has been placed in those resulting from inborn errors of immunity …

Substantial amounts of data have been reported showing a role for immunomodulation of
epithelial function (particularly ion secretion and permeability) using animal models of …

Although the precise etiologies of inflammatory bowel disease (IBD)(ulcerative colitis and
Crohn's disease) remain obscure, several reports have indicated that dysfunction of the …

Immune regulation plays a crucial role in human health and disease. Inflammatory bowel
disease (IBD) is a chronic relapse bowel disease with an increasing incidence worldwide …

Inflammatory bowel disease (IBD), typified by ulcerative colitis and Crohn's disease, has an
aetiology that appears to possess both genetic and environmental components. A number of …

AETIOPATHOGENESIS OF IBD The gastrointestinal associated lymphoid tissue (GALT) is
the largest and most complex immunological organ of the body, and must be capable of …

Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, has
multifactorial aetiology with complex interactions between genetic and environmental …

While barrier function and the effects of the intestinal microbiome have only recently moved
into the focus of inflammatory bowel disease research, the role of the innate and the …