[HTML][HTML] Regulatory mechanisms of immune responses to intestinal bacteria

K Honda, K Takeda - Mucosal immunology, 2009 - Elsevier
The intestinal mucosa allows the residence of trillions of bacteria with which it interacts
dynamically. To establish and maintain a mutually beneficial relationship, the mucosal …

Monogenic intestinal epithelium defects and the development of inflammatory bowel disease

G Leung, AM Muise - Physiology, 2018 - journals.physiology.org
The incidence of inflammatory bowel disease (IBD) is increasing worldwide, most notably in
young children. The development of disease is a combination of several factors, including …

[HTML][HTML] Gut permeability and mucosal inflammation: bad, good or context dependent

R Ahmad, MF Sorrell, SK Batra, P Dhawan… - Mucosal …, 2017 - Elsevier
Inflammatory bowel disease (IBD) is a multifactorial disease. A breach in the mucosal
barrier, otherwise known as “leaky gut,” is alleged to promote mucosal inflammation by …

Epigenetic regulation of T helper cells and intestinal pathogenicity

Y Hagihara, Y Yoshimatsu, Y Mikami, Y Takada… - Seminars in …, 2019 - Springer
Inflammatory bowel diseases (IBDs) are characterized by relapsing and remitting chronic
intestinal inflammation. Previous studies have demonstrated the contributions of genetic …

Mouse models of inflammatory bowel disease

S Wirtz, MF Neurath - Advanced drug delivery reviews, 2007 - Elsevier
Animal models of intestinal inflammation are indispensable for our understanding of the
pathogenesis of Crohn disease and Ulcerative colitis, the idiopathic forms of inflammatory …

Immunology of inflammatory bowel disease and molecular targets for biologics

M Dave, KA Papadakis… - Gastroenterology Clinics, 2014 - gastro.theclinics.com
Immunology of Inflammatory Bowel Disease and Molecular Targets for Biologics -
Gastroenterology Clinics Skip to Main Content Skip to Main Menu Advertisement Gastroenterology …

Immunopathogenesis of inflammatory bowel disease

I Dotan, L Mayer - Current opinion in Gastroenterology, 2002 - journals.lww.com
Inflammatory bowel disease (IBD) is characterized by inflammation that results from the
interaction between the various components of the mucosal immune system and the …

Macrophage immunometabolism in inflammatory bowel diseases: from pathogenesis to therapy

X Pan, Q Zhu, LL Pan, J Sun - Pharmacology & therapeutics, 2022 - Elsevier
Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is a
chronic relapsing inflammatory disease of the gastrointestinal tract that closely related to …

Intestinal innate immune cells in gut homeostasis and immunosurveillance

E Tomasello, S Bedoui - Immunology and cell biology, 2013 - Wiley Online Library
The March 2013 issue of Immunology and Cell Biology contains a special feature that
focuses on the role of the intestinal epithelial barrier and innate immune cells, examines …

[HTML][HTML] The digestive system and autoimmunity

L Sun, B Zhang - BMC immunology, 2023 - Springer
Digestive autoimmune conditions are a growing challenge to global health. Risk factors
associated with autoimmune digestive diseases are complex, including genetic variation …