The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans

BJ Loftus, E Fung, P Roncaglia, D Rowley, P Amedeo… - Science, 2005 - science.org
Cryptococcus neoformans is a basidiomycetous yeast ubiquitous in the environment, a
model for fungal pathogenesis, and an opportunistic human pathogen of global importance …

Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans

A Idnurm, YS Bahn, K Nielsen, X Lin… - Nature Reviews …, 2005 - nature.com
Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

Genetics of Cryptococcus neoformans

CM Hull, J Heitman - Annual review of genetics, 2002 - annualreviews.org
▪ Abstract Cryptococcus neoformans is a pathogenic fungus that primarily afflicts
immunocompromised patients, infecting the central nervous system to cause …

Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence …

G Janbon, KL Ormerod, D Paulet, EJ Byrnes III… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

Recent Evolution of the Human Pathogen Cryptococcus neoformans by Intervarietal Transfer of a 14-Gene Fragment

LA Kavanaugh, JA Fraser… - Molecular biology and …, 2006 - academic.oup.com
The availability of the whole-genome sequence from the 2 known varieties of the human
pathogenic fungus Cryptococcus neoformans provides an opportunity to study the relative …

Cryptococcus neoformans: the yeast that likes it hot

JR Perfect - FEMS yeast research, 2006 - academic.oup.com
The ability of fungi to grow well at mammalian body temperatures is a fundamental
characteristic of invasive human fungal pathogens. Cryptococcus neoformans, with its …

DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

DA Magditch, TB Liu, C Xue, A Idnurm - 2012 - journals.plos.org
The disease cryptococcosis, caused by the fungus Cryptococcus neoformans, is acquired
directly from environmental exposure rather than transmitted person-to-person. One …

Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii

Y Chen, RA Farrer, C Giamberardino, S Sakthikumar… - MBio, 2017 - Am Soc Microbiol
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …

Multiple gene genealogies reveal recent dispersion and hybridization in the human pathogenic fungus Cryptococcus neoformans

J Xu, R Vilgalys, TG Mitchell - Molecular Ecology, 2000 - Wiley Online Library
Cryptococcus neoformans (= Filobasidiella neoformans) is a significant emerging fungal
pathogen of humans. To understand the evolution of this pathogen, 34 strains were obtained …

Cryptococcus neoformans: A sugar-coated killer with designer genes

JR Perfect - FEMS Immunology & Medical Microbiology, 2005 - academic.oup.com
Cryptococcus neoformans has become a common central nervous system pathogen as the
immunocompromised populations enlarge world-wide. This encapsulated yeast has …