Biosynthesis and degradation of canine placental prostaglandins: prepartum changes in expression and function of prostaglandin F2alpha-synthase (PGFS, AKR1C3) …

A Gram, U Büchler, A Boos, B Hoffmann… - Biology of …, 2013 - academic.oup.com
There is no distinct explanation of the mechanism for the prepartal prostaglandin F2alpha
(PGF2alpha) increase in pregnant dogs. Although the PGF2alpha-synthase (PGFS …

Canine placental prostaglandin E2 synthase: expression, localization, and biological functions in providing substrates for prepartum PGF2alpha synthesis

A Gram, B Fox, U Büchler, A Boos… - Biology of …, 2014 - academic.oup.com
The prepartum output of PGF2alpha in the bitch is associated with increased placental
PGE2-synthase (PTGES) mRNA levels. Contrasting with this is a decreased expression of …

Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition

MP Kowalewski, HB Beceriklisoy, C Pfarrer… - …, 2010 - rep.bioscientifica.com
Expression of cyclooxygenase 2 (COX2, now known as PTGS2), prostaglandin E2 synthase
(PTGES, PGES), and prostaglandin F2α synthase (PGFS), of the respective receptors …

Comprehensive analysis of prostaglandin metabolic enzyme expression during pregnancy and the characterization of AKR1B1 as a prostaglandin F synthase at the …

H Seo, Y Choi, J Shim, I Yoo, H Ka - Biology of reproduction, 2014 - academic.oup.com
Prostaglandins (PGs) are important lipid mediators regulating various reproductive
processes in many species. In pigs, the expression pattern of PGE2 and PGF2α metabolic …

Interplacental uterine expression of genes involved in prostaglandin synthesis during canine pregnancy and at induced prepartum luteolysis/abortion

MP Kowalewski, E Kautz, E Högger… - Reproductive Biology …, 2014 - Springer
Background In the non-pregnant dog, ovarian cyclicity is independent of a uterine luteolysin.
This is in contrast to pregnant animals where a prepartum increase of luteolytic PGF2α …

Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation

W Gibb, SG Matthews, JRG Challis - Biology of reproduction, 1996 - academic.oup.com
In numerous animal species, increased prostaglandin output by intrauterine tissues occurs
in association with parturition. In the sheep, prostaglandin H synthase (PGHS) is particularly …

Ontogeny and Regulation of Ovine Placental Prostaglandin E2 Synthase

RL Martin, WL Whittle, AC Holloway… - Biology of …, 2002 - academic.oup.com
Recent evidence suggests that ovine placental output of prostaglandin (PG) E2 rises
through late gestation partly because of a direct effect of cortisol on PGH2 synthase 2 (PGHS …

Differential expression of prostaglandin (PG) synthesis enzymes in conceptus during peri-implantation period and endometrial expression of carbonyl reductase/PG 9 …

A Waclawik, AJ Ziecik - Journal of Endocrinology, 2007 - joe.bioscientifica.com
Prostaglandins (PGs) play a pivotal role in luteolysis, maternal recognition of pregnancy,
and implantation. In many species, including pigs, both conceptus (embryo and associated …

Immunohistochemical localization of prostaglandin H synthase in the sheep placenta from early pregnancy to term

DP Boshier, RA Jacobs, VKM Han, W Smith… - Biology of …, 1991 - academic.oup.com
Prostaglandin H synthase (PGHS) activity within intrauterine tissues is considered to
catalyze a critical step in prostaglandin (PG) biosynthesis at parturition. In sheep, the …

[PDF][PDF] Quantitative characterization of prostaglandins in the uterus of early pregnant cattle

SE Ulbrich, K Schulke, AE Groebner… - …, 2009 - scholar.archive.org
Prostaglandins (PGs) are important regulators of reproductive processes including early
embryonic development. We analyzed the most relevant PG in bovine uteri at different …