Single-molecule FRET investigation of binding and the comparative effect of DNA architectural proteins on Holliday junction conformational dynamics
F Islam - Biophysical Journal, 2024 - cell.com
Integration host factor (IHF) of E. coli is a nucleoid-associated protein, pivotal in DNA
packaging, viral DNA integration, and recombination. IHF binds to duplex DNA, forming a 13 …
packaging, viral DNA integration, and recombination. IHF binds to duplex DNA, forming a 13 …
Molecular Insight into the Structural Dynamics of Holliday Junctions Modulated by Integration Host Factor
F Islam, PP Mishra - The Journal of Physical Chemistry B, 2024 - ACS Publications
The integration host factor (IHF) in Escherichia coli is a nucleoid-associated protein with
multifaceted roles that encompass DNA packaging, viral DNA integration, and …
multifaceted roles that encompass DNA packaging, viral DNA integration, and …
Unveiling the Holliday junction conformational dynamics upon binding with architectural proteins IHF
F Islam, PP Mishra - bioRxiv, 2023 - biorxiv.org
Integration host factor (IHF) is a vital nucleoid-associated protein that binds strongly to a 13-
base-pair consensus sequence, inducing a significant bend of approximately 160° upon …
base-pair consensus sequence, inducing a significant bend of approximately 160° upon …
Establishing a Single-Molecule FRET System for Studying DNA-Protein Interactions
Integration host factor (IHF) is an E. Coli architectural protein that exists as a heterodimer,
composed of an α and β subunit. Originally identified in the integration of bacterial phage …
composed of an α and β subunit. Originally identified in the integration of bacterial phage …
Integration Host Factor Binds DNA Holliday Junctions
Integration host factor (IHF) is a nucleoid-associated protein involved in DNA packaging,
integration of viral DNA and recombination. IHF binds with nanomolar affinity to duplex DNA …
integration of viral DNA and recombination. IHF binds with nanomolar affinity to duplex DNA …
[HTML][HTML] Site-Specific Investigation of DNA Holliday Junction Dynamics and Structure with 6-Methylisoxanthopterin, a Fluorescent Guanine Analog
Z Lombardo, I Mukerji - bioRxiv, 2024 - ncbi.nlm.nih.gov
Abstract DNA Holliday Junction (HJ) formation and resolution is requisite for maintaining
genomic stability in processes such as replication fork reversal and double-strand break …
genomic stability in processes such as replication fork reversal and double-strand break …
Atomistic picture of opening–closing dynamics of DNA Holliday junction obtained by molecular simulations
Holliday junction (HJ) is a noncanonical four-way DNA structure with a prominent role in
DNA repair, recombination, and DNA nanotechnology. By rearranging its four arms, HJ can …
DNA repair, recombination, and DNA nanotechnology. By rearranging its four arms, HJ can …
Direct observation of the external force mediated conformational dynamics of an IHF bound Holliday junction
We have investigated the isomerization dynamics and plausible energy landscape of 4-way
Holliday junctions (4WHJs) bound to integration host factor (IHF, a DNA binding protein) …
Holliday junctions (4WHJs) bound to integration host factor (IHF, a DNA binding protein) …
Physical organization of DNA by multiple non-specific DNA-binding modes of integration host factor (IHF)
The integration host factor (IHF) is an abundant nucleoid-associated protein and an
essential co-factor for phage λ site-specific recombination and gene regulation in E. coli …
essential co-factor for phage λ site-specific recombination and gene regulation in E. coli …
Structure, dynamics, and branch migration of a DNA Holliday junction: a single-molecule fluorescence and modeling study
MA Karymov, M Chinnaraj, A Bogdanov… - Biophysical journal, 2008 - cell.com
The Holliday junction (HJ) is a central intermediate of various genetic processes, including
homologous and site-specific DNA recombination and DNA replication. Elucidating the …
homologous and site-specific DNA recombination and DNA replication. Elucidating the …