As antibiotic resistance increases worldwide, there is an increasing pressure to develop
novel classes of antimicrobial compounds to fight infectious disease. Peptide therapeutics …

Background Infections caused by drug-resistant strains of Acinetobacter baumannii and
Pseudomonas aeruginosa are now a global problem that requires the immediate …

Background NP4P is a synthetic peptide derived from a natural, non-antimicrobial peptide
fragment (pro-region of nematode cecropin P4) by substitution of all acidic amino acid …

The discovery of penicillin and the tremendous success achieved in preventing fatalities due
to microbial infections by using it as a therapeutic antibiotic was perhaps the starting point of …

The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Because of the emergence of antibiotic‐resistant pathogens worldwide, a number of
infectious diseases have become difficult to treat. This threatening situation is worsened by …

The book will provide an overview of the advancement of fundamental knowledge and
applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and …

Introduction: The recent dramatic increase in the incidence of antimicrobial resistance has
been recognized by organizations such as the United Nations and World Health …

The introduction of the first antibiotic (penicillin) by Sir Alexander Fleming in 1928 was a
huge milestone in the treatment of infectious diseases. Unfortunately, after several years the …

Antimicrobial peptides are key components of native immunity. Unlike most common small-
molecule antibiotics, antimicrobial peptides have been refined by evolution to work …