A supramodal accumulation-to-bound signal that determines perceptual decisions in humans

RG O'connell, PM Dockree, SP Kelly - Nature neuroscience, 2012 - nature.com
In theoretical accounts of perceptual decision-making, a decision variable integrates noisy
sensory evidence and determines action through a boundary-crossing criterion. Signals …

Abstract and effector-selective decision signals exhibit qualitatively distinct dynamics before delayed perceptual reports

DM Twomey, SP Kelly, RG O'Connell - Journal of Neuroscience, 2016 - Soc Neuroscience
Electrophysiological research has isolated neural signatures of decision formation in a
variety of brain regions. Studies in rodents and monkeys have focused primarily on effector …

Internal and external influences on the rate of sensory evidence accumulation in the human brain

SP Kelly, RG O'Connell - Journal of Neuroscience, 2013 - Soc Neuroscience
We frequently need to make timely decisions based on sensory evidence that is weak,
ambiguous, or noisy resulting from conditions in the external environment (eg, a cluttered …

Domain general mechanisms of perceptual decision making in human cortex

TC Ho, S Brown, JT Serences - Journal of Neuroscience, 2009 - Soc Neuroscience
To successfully interact with objects in the environment, sensory evidence must be
continuously acquired, interpreted, and used to guide appropriate motor responses. For …

Deliberation in the motor system: reflex gains track evolving evidence leading to a decision

LPJ Selen, MN Shadlen, DM Wolpert - Journal of Neuroscience, 2012 - Soc Neuroscience
Both decision making and sensorimotor control require real-time processing of noisy
information streams. Historically these processes were thought to operate sequentially …

Decoding and perturbing decision states in real time

D Peixoto, JR Verhein, R Kiani, JC Kao, P Nuyujukian… - Nature, 2021 - nature.com
In dynamic environments, subjects often integrate multiple samples of a signal and combine
them to reach a categorical judgment. The process of deliberation can be described by a …

Neural dynamics of choice: single-trial analysis of decision-related activity in parietal cortex

A Bollimunta, D Totten, J Ditterich - Journal of Neuroscience, 2012 - Soc Neuroscience
Previous neurophysiological studies of perceptual decision-making have focused on single-
unit activity, providing insufficient information about how individual decisions are …

Neurophysiology of human perceptual decision-making

RG O'Connell, SP Kelly - Annual Review of Neuroscience, 2021 - annualreviews.org
The discovery of neural signals that reflect the dynamics of perceptual decision formation
has had a considerable impact. Not only do such signals enable detailed investigations of …

Decision threshold modulation in the human brain

P Domenech, JC Dreher - Journal of Neuroscience, 2010 - Soc Neuroscience
Perceptual decisions are made when sensory evidence accumulated over time reaches a
decision threshold. Because decisions are also guided by prior information, one important …

The neural processes underlying perceptual decision making in humans: recent progress and future directions

SP Kelly, RG O'Connell - Journal of Physiology-Paris, 2015 - Elsevier
In the last two decades, animal neurophysiology research has made great strides towards
explaining how the brain can enable adaptive action in the face of noisy sensory …