Isolation and properties of secretory granules from rat islets of Langerhans: I. Isolation of a secretory granule fraction
SL Howell, CJ Fink, PE Lacy - The Journal of Cell Biology, 1969 - ncbi.nlm.nih.gov
A method has been devised for the isolation of a secretory granule fraction from isolated rat
islets of Langerhans. The islets were homogenized in buffered sucrose, and the …
islets of Langerhans. The islets were homogenized in buffered sucrose, and the …
ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS: III. Studies of the Stability of the Isolated Beta Granules
SL Howell, DA Young, PE Lacy - The Journal of Cell Biology, 1969 - ncbi.nlm.nih.gov
A partially purified secretory granule fraction, isolated from rat islets of Langerhans by
differential centrifugation, was used for investigating the stability of the beta granules during …
differential centrifugation, was used for investigating the stability of the beta granules during …
Electron microscopic and fluorescent antibody studies on islets of Langerhans
PE Lacy - Experimental Cell Research, 1959 - Elsevier
The ultrastructure of the beta granules is distinctly different in the islets of the rat, dog, cat,
rabbit, guinea pig and chicken. The variations are so characteristic that each species can be …
rabbit, guinea pig and chicken. The variations are so characteristic that each species can be …
Isolation and properties of secretory granules from rat islets of Langerhans: II. Ultrastructure of the beta granule
MH Greider, SL Howell, PE Lacy - The Journal of cell biology, 1969 - ncbi.nlm.nih.gov
Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic
acid had, in negatively stained images, a 50-A periodicity. This periodicity was also …
acid had, in negatively stained images, a 50-A periodicity. This periodicity was also …
Ultrastructure of the A-cells of cat islets of Langerhans following sympathetic stimulation of glucagon secretion
AC Esterhuizen, SL Howell - The Journal of Cell Biology, 1970 - ncbi.nlm.nih.gov
A previous ultrastructural study of the mechanism ofglucagon secretion from the alpha cells
of rabbit islets of Langerhans has suggested that the agranules disintegrate, forming small …
of rabbit islets of Langerhans has suggested that the agranules disintegrate, forming small …
Secretory granule formation and release in rabbit pancreatic A-cells
SS Lazarus, S Shapiro, BW Volk - Diabetes, 1968 - Am Diabetes Assoc
A-cells of the islets of Langerhans from normal rabbits as well as rabbits treated with insulin,
cortisone, or tolbutamide or subjected to a semistarvation diet were studied by light and …
cortisone, or tolbutamide or subjected to a semistarvation diet were studied by light and …
[HTML][HTML] Studies on the molecular organization of rat insulin secretory granules.
J Michael, R Carroll, HH Swift, DF Steiner - Journal of Biological Chemistry, 1987 - Elsevier
Secretory granule-enriched fractions prepared from isolated rat islets of Langerhans,
previously labeled in culture for 18 h with [3H] leucine, have been lysed and separated into …
previously labeled in culture for 18 h with [3H] leucine, have been lysed and separated into …
Preparation and characterization of plasma membrane-enriched fractions from rat pancreatic islets.
A Lernmark, A Nathans, DF Steiner - The Journal of cell biology, 1976 - rupress.org
Methods have been developed for the isolation on a semi-micro scale of a plasma
membrane-enriched fraction from rat islets of Langerhans. An important feature of these …
membrane-enriched fraction from rat islets of Langerhans. An important feature of these …
Method for the isolation of intact islets of Langerhans from the rat pancreas
PE Lacy, M Kostianovsky - Diabetes, 1967 - Am Diabetes Assoc
A simple method for the isolation of intact islets from the normal rat pancreas is described.
The method is based upon disruption of the acinar parenchyma by injecting Hanks solution …
The method is based upon disruption of the acinar parenchyma by injecting Hanks solution …
The comparative ultrastructure of the pancreatic islet of Langerhans
T Sato, L Herman, PJ Fitzgerald - General and Comparative Endocrinology, 1966 - Elsevier
A comparative study of the pancreatic islets of Langerhans was undertaken in which
correlative thick-thin sectioning techniques for light and electron microscopy were used. This …
correlative thick-thin sectioning techniques for light and electron microscopy were used. This …