[HTML][HTML] New frontiers in neurodegeneration and regeneration associated with brain-derived neurotrophic factor and the rs6265 single nucleotide polymorphism

CA Szarowicz, K Steece-Collier… - International journal of …, 2022 - mdpi.com
Brain-derived neurotrophic factor is an extensively studied neurotrophin implicated in the
pathology of multiple neurodegenerative and psychiatric disorders including, but not limited …

[HTML][HTML] BDNF therapeutic mechanisms in neuropsychiatric disorders

AH Bazzari, FH Bazzari - International Journal of Molecular Sciences, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is the most abundant neurotrophin in the adult
brain and functions as both a primary neurotrophic signal and a neuromodulator. It serves …

Brain-derived neurotrophic factor (BDNF): novel insights into regulation and genetic variation

M Notaras, M van den Buuse - The Neuroscientist, 2019 - journals.sagepub.com
Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that
now spans 35 years of research. While all neurotrophins share considerable overlap in …

[HTML][HTML] Critical Issues in BDNF Val66Met Genetic Studies of Neuropsychiatric Disorders

SJ Tsai - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Neurotrophins have been implicated in the pathophysiology of many neuropsychiatric
diseases. Brain-derived neurotrophic factor (BDNF) is the most abundant and widely …

Brain derived neurotrophic factor: a novel neurotrophin involved in psychiatric and neurological disorders

S Balaratnasingam, A Janca - Pharmacology & therapeutics, 2012 - Elsevier
Brain Derived Neurotrophic Factor (BDNF) is a unique member of the neurotrophin family
with potent and plethoric effects on the proliferation, differentiation, survival and death of …

[HTML][HTML] BDNF polymorphism: a review of its diagnostic and clinical relevance in neurodegenerative disorders

T Shen, Y You, C Joseph, M Mirzaei… - Aging and …, 2018 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF) has a unique role in the neuronal development,
differentiation, and survival in the developing and adult nervous system. A common single …

[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Brain-derived neurotrophic factor as a drug target for CNS disorders

S Pezet, M Malcangio - Expert opinion on therapeutic targets, 2004 - Taylor & Francis
Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family of trophic
factors. BDNF is widely and abundantly expressed in the CNS and is available to some …

[HTML][HTML] The BDNF Val66Met Polymorphism Modulates Resilience of Neurological Functioning to Brain Ageing and Dementia: A Narrative Review

DT Brown, JC Vickers, KE Stuart, K Cechova, DD Ward - Brain Sciences, 2020 - mdpi.com
Brain-derived neurotropic factor (BDNF) is an abundant and multi-function neurotrophin in
the brain. It is released following neuronal activity and is believed to be particularly important …

[HTML][HTML] Genetic and epigenetic regulation of the brain-derived neurotrophic factor in the central nervous system

GA Martínez-Levy, CS Cruz-Fuentes - The Yale journal of biology …, 2014 - ncbi.nlm.nih.gov
The BDNF is required for the development and proper function of the central nervous
system, where it is involved in a variety of neural and molecular events relevant to cognition …