Yeast Nrd1, Nab3, and Sen1 transcriptome-wide binding maps suggest multiple roles in post-transcriptional RNA processing
N Jamonnak, TJ Creamer, MM Darby, P Schaughency… - Rna, 2011 - rnajournal.cshlp.org
RNA polymerase II transcribes both coding and noncoding genes, and termination of these
different classes of transcripts is facilitated by different sets of termination factors. Pre …
different classes of transcripts is facilitated by different sets of termination factors. Pre …
Transcriptome-Wide Binding Sites for Components of the Saccharomyces cerevisiae Non-Poly(A) Termination Pathway: Nrd1, Nab3, and Sen1
TJ Creamer, MM Darby, N Jamonnak… - PLoS …, 2011 - journals.plos.org
RNA polymerase II synthesizes a diverse set of transcripts including both protein-coding and
non-coding RNAs. One major difference between these two classes of transcripts is the …
non-coding RNAs. One major difference between these two classes of transcripts is the …
Pervasive transcription: a controlled risk
T Villa, O Porrua - The FEBS Journal, 2023 - Wiley Online Library
Transcriptome‐wide interrogation of eukaryotic genomes has unveiled the pervasive nature
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …
of RNA polymerase II transcription. Virtually, any DNA region with an accessible chromatin …
Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II …
EJ Steinmetz, DA Brow - Proceedings of the National …, 1998 - National Acad Sciences
Nrd1 is an essential yeast protein of unknown function that has an RNA recognition motif
(RRM) in its carboxyl half and a putative RNA polymerase II-binding domain, the CTD …
(RRM) in its carboxyl half and a putative RNA polymerase II-binding domain, the CTD …
The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective
B Chaves-Arquero… - Biochemical Society …, 2023 - portlandpress.com
A substantial part of living cells activity involves transcription regulation. The RNA
polymerases responsible for this job need to know 'where/when'to start and stop in the …
polymerases responsible for this job need to know 'where/when'to start and stop in the …
Common genomic elements promote transcriptional and DNA replication roadblocks
K Roy, J Gabunilas, A Gillespie, D Ngo… - Genome …, 2016 - genome.cshlp.org
RNA polymerase II (Pol II) transcription termination by the Nrd1p-Nab3p-Sen1p (NNS)
pathway is critical for the production of stable noncoding RNAs and the control of pervasive …
pathway is critical for the production of stable noncoding RNAs and the control of pervasive …
Widespread bidirectional promoters are the major source of cryptic transcripts in yeast
Pervasive and hidden transcription is widespread in eukaryotes,,,, but its global level, the
mechanisms from which it originates and its functional significance are unclear. Cryptic …
mechanisms from which it originates and its functional significance are unclear. Cryptic …
Unravelling the means to an end: RNA polymerase II transcription termination
JN Kuehner, EL Pearson, C Moore - Nature reviews Molecular cell …, 2011 - nature.com
The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
(Pol II)-mediated transcription, and termination of its activity is necessary to partition the …
Termination of cryptic unstable transcripts is directed by yeast RNA-binding proteins Nrd1 and Nab3
JT Arigo, DE Eyler, KL Carroll, JL Corden - Molecular cell, 2006 - cell.com
Studies of yeast transcription have revealed the widespread distribution of intergenic RNA
polymerase II transcripts. These cryptic unstable transcripts (CUTs) are rapidly degraded by …
polymerase II transcripts. These cryptic unstable transcripts (CUTs) are rapidly degraded by …
Terminating transcription in yeast: whether to be a'nerd'or a'rat'
AG Rondon, HE Mischo, NJ Proudfoot - Nature structural & molecular …, 2008 - nature.com
Transcriptional termination by RNA polymerase II in yeast occurs by two different pathways:
stable or cryptic unstable transcripts use the Nrd1 complex, whereas mRNA uses 3 …
stable or cryptic unstable transcripts use the Nrd1 complex, whereas mRNA uses 3 …