[HTML][HTML] Receptor tyrosine kinases and their signaling pathways as therapeutic targets of curcumin in cancer

S Sudhesh Dev, SA Zainal Abidin… - Frontiers in …, 2021 - frontiersin.org
Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

[HTML][HTML] Curcumin―the paradigm of a multi-target natural compound with applications in cancer prevention and treatment

MH Teiten, S Eifes, M Dicato, M Diederich - Toxins, 2010 - mdpi.com
As cancer is a multifactor disease, it may require treatment with compounds able to target
multiple intracellular components. We summarize here how curcumin is able to modulate …

Multifunctional curcumin mediate multitherapeutic effects

A Shehzad, M Qureshi, MN Anwar… - Journal of food …, 2017 - Wiley Online Library
Inflammation can promote the development of arthritis, obesity, cardiovascular, type II
diabetes, pancreatitis, metabolic and neurodegenerative diseases, and certain types of …

[PDF][PDF] Curcumin: a potential cancer chemopreventive agent through suppressing NF-κB signaling

CL Lin, JK Lin - J Cancer Mol, 2008 - researchgate.net
Curcumin[(1E, 6E)-1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione] is an
orange-yellow active component from the herb Curcuma longa (usually known as turmeric) …

Recent updates on clinical developments of curcumin and its derivatives

P Joshi, A Bisht, A Paliwal, J Dwivedi… - Phytotherapy …, 2023 - Wiley Online Library
Curcumin, a natural polyphenol, derived from Curcuma longa L. is extensively studied by
various researchers across the globe and has established its immense potential in the …

[HTML][HTML] Bioactivity, health benefits, and related molecular mechanisms of curcumin: Current progress, challenges, and perspectives

XY Xu, X Meng, S Li, RY Gan, Y Li, HB Li - Nutrients, 2018 - mdpi.com
Curcumin is a principal curcuminoid of turmeric (Curcuma longa), which is commonly used
as a spice in cooking and a yellow pigment in the food processing industry. Recent studies …

[HTML][HTML] Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy

M Mimeault, SK Batra - Chinese medicine, 2011 - Springer
Curcumin has attracted great attention in the therapeutic arsenal in clinical oncology due to
its chemopreventive, antitumoral, radiosensibilizing and chemosensibilizing activities …

Molecular targets of curcumin

JK Lin - The molecular targets and therapeutic uses of …, 2007 - Springer
Curcumin possesses anti-inflammatory activity and is a potent inhibitor of reactive-oxygen-
generating enzymes such as lipoxygenase/cyclooxygenase, xanthine dehydrogenase …

[PDF][PDF] Anticancer potential of curcumin: preclinical and clinical studies

BB Aggarwal, A Kumar, AC Bharti - Anticancer research, 2003 - curcuminresearch.org
Curcumin (diferuloylmethane) is a polyphenol derived from the plant Curcuma longa,
commonly called turmeric. Extensive research over the last 50 years has indicated this …

[HTML][HTML] Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses

BB Aggarwal, L Deb, S Prasad - Molecules, 2014 - mdpi.com
Curcumin (diferuloylmethane), a golden pigment from turmeric, has been linked with
antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, and antidiabetic properties …