Retroviral gene expression generally depends on a full-length transcript that initiates in the
5'long terminal repeat (LTR), which is either unspliced or alternatively spliced. We and …

The production of antisense transcripts from the 3′ long terminal repeat (LTR) in human T-
lymphotropic retroviruses has now been clearly demonstrated. After the identification of the …

The human T-cell lymphotropic virus (HTLV) retrovirus family is composed of the well-known
HTLV type 1 (HTLV-1) and HTLV-2 and the most recently discovered HTLV-3 and HTLV-4 …

The complex human T-cell leukemia virus type 1 (HTLV-1) retrovirus encodes several
proteins that are unique to the virus within its 3′-end region. Among them, the viral …

Several studies have recently demonstrated the existence of human T-cell leukemia virus
type 1 (HTLV-1) antisense transcripts, which allow the synthesis of the newly described HBZ …

Human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper factor (HBZ) is transcribed
from the antisense genomic DNA strand and functions differently in its RNA and protein …

The human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus that integrates randomly into
the T-cell genome. Two long terminal repeats (LTRs) flank the integrated provirus. The …

IMPORTANCE The chromosomally integrated form of the retrovirus human T-cell leukemia
virus type 1 (HTLV-1) contains identical DNA sequences, known as long terminal repeats …

Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) retroviruses infect T
lymphocytes. The minus strand of the HTLV-1 genome encodes HBZ, a protein that could …

Human T cell leukemia virus type I (HTLV-I) causes adult T cell leukemia (ATL) in 2–5% of
carriers after a long latent period. An HTLV-I encoded protein, Tax, induces proliferation and …