[HTML][HTML] ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper
An increasing number of studies are describing potential uses of circulating tumour DNA
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …
(ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area …
[HTML][HTML] The promise of circulating tumor DNA (ctDNA) in the management of early-stage colon cancer: a critical review
Simple Summary Currently, the treatment for localized colon cancer consists of surgery and,
if the presence of residual cancer cells is suspected, chemotherapy following the surgery …
if the presence of residual cancer cells is suspected, chemotherapy following the surgery …
Clinical application of circulating tumour DNA in colorectal cancer
M Loft, YH To, P Gibbs, J Tie - The Lancet Gastroenterology & …, 2023 - thelancet.com
Liquid biopsies that detect circulating tumour DNA (ctDNA) have the potential to
revolutionise the personalised management of colorectal cancer. For patients with early …
revolutionise the personalised management of colorectal cancer. For patients with early …
Circulating tumor DNA: an emerging tool in gastrointestinal cancers
Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that
has come from primary or metastatic cancer sites. Neoplasm-specific genetic and epigenetic …
has come from primary or metastatic cancer sites. Neoplasm-specific genetic and epigenetic …
[HTML][HTML] Circulating tumor DNA in precision oncology and its applications in colorectal cancer
MF Arisi, E Dotan, SV Fernandez - International Journal of Molecular …, 2022 - mdpi.com
Circulating tumor DNA (ctDNA) is a component of cell-free DNA (cfDNA) that is shed by
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …
[HTML][HTML] The use of circulating tumor DNA to monitor and predict response to treatment in colorectal cancer
M Reece, H Saluja, P Hollington, CS Karapetis… - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer is one of the most common cancers worldwide and has a
high mortality rate following disease recurrence. Treatment efficacy is maximized by …
high mortality rate following disease recurrence. Treatment efficacy is maximized by …
Using circulating tumor DNA in colorectal cancer: current and evolving practices
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
[HTML][HTML] Circulating tumor DNA detection: A potential tool for colorectal cancer management
H Li, C Jing, J Wu, J Ni, H Sha, X Xu… - Oncology …, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …
[HTML][HTML] ctDNA and adjuvant therapy for colorectal cancer: time to re-invent our treatment paradigm
M Naidoo, P Gibbs, J Tie - Cancers, 2021 - mdpi.com
Simple Summary There is currently a lack of useful tests to detect microscopic residual
disease in patients who have undergone surgery to remove their bowel cancer. This inability …
disease in patients who have undergone surgery to remove their bowel cancer. This inability …
Early evaluation of circulating tumor DNA as marker of therapeutic efficacy in metastatic colorectal cancer patients (PLACOL study)
F Garlan, P Laurent-Puig, D Sefrioui, N Siauve… - Clinical Cancer …, 2017 - AACR
Purpose: Markers of chemotherapy efficacy in metastatic colorectal cancer (mCRC) are
essential for optimization of treatment strategies. We evaluated the applicability of early …
essential for optimization of treatment strategies. We evaluated the applicability of early …