The ratio of the area under the free (unbound) concentration–time curve to minimum
inhibitory concentration (fAUC/MIC) was proposed to be the pharmacokinetic …

Background Colistin is being increasingly used for treatment of infections caused by
multidrug-resistant Gram-negative bacteria, including Acinetobacter baumannii. Methods …

The clinical characteristics of patients with colistin-resistant Acinetobacter baumannii
bacteraemia have been documented, but those of patients with bacteraemia caused by …

Objective: This study investigated the minimum inhibitory concentration (MIC) values and in
vitro activity of colistin in combination with tigecycline against carbapenem-resistant …

Introduction: Colistin use has increased over the last ten years because of multidrug-
resistant microorganisms. The aim of this study was to compare the clinical and …

Background Nosocomial infections due to multi-drug resistant Acinetobacter baumannii are
often treated with colistin, but there are few data comparing its safety and efficacy with other …

To the Editor—In an article recently published in the Journal, Lopez-Rojas et al [1]
demonstrated that an in vitro mutant of Acinetobacter baumannii resistant to colistin had …

Increased use of colistin in a clinical setting had resulted in the emergence of colistin-
resistant (CoR) Acinetobacter baumannii. Combination therapy has been studied as a new …

The objective of this study was to determine the efficacy of systemic colistin therapy in the
treatment of nosocomial infections caused by multidrug-resistant Acinetobacter baumannii …

Colistin is one of the most effective alternatives for treating Acinetobacter baumannii
infections. The aim of this study was to determine colistin resistance and heteroresistance …