Alzheimer s disease and oxidative stress: a review

M Pohanka - Current medicinal chemistry, 2014 - ingentaconnect.com
Alzheimer´ s disease (AD) is a neurodegenerative disorder with no known cure and rapid
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

G Perry, PI Moreira, MS Santos… - CNS & Neurological …, 2008 - ingentaconnect.com
Oxidative stress occurs early in the progression of Alzheimer disease, significantly before
the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. All …

Oxidative stress and amyloid beta toxicity in Alzheimer's disease: intervention in a complex relationship by antioxidants

S Chakrabarti, M Sinha, I G. Thakurta… - Current Medicinal …, 2013 - benthamdirect.com
The elucidation of the intriguing relationship between oxidative stress and Alzheimer's
disease is crucial to understand the pathogenesis of the disease as also to design a suitable …

Oxidative stress in Alzheimer's disease: molecular hallmarks of underlying vulnerability

MS Uddin, MT Kabir - Biological, Diagnostic and Therapeutic Advances in …, 2019 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …

Oxidative stress and the pathogenesis of Alzheimer′ s disease

Y Zhao, B Zhao - Oxidative medicine and cellular longevity, 2013 - Wiley Online Library
Alzheimer′ s disease (AD) is the most common neurodegenerative disease that causes
dementia in the elderly. Patients with AD suffer a gradual deterioration of memory and other …

Oxidative stress in Alzheimer's disease: implications for prevention and therapy

C Behl - Alzheimer's Disease: Cellular and Molecular Aspects of …, 2005 - Springer
Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …

Future therapeutic perspectives into the Alzheimer's disease targeting the oxidative stress hypothesis

JP Teixeira, AA de Castro, FV Soares, EFF da Cunha… - Molecules, 2019 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease that is usually accompanied by
aging, increasingly being the most common cause of dementia in the elderly. This disorder …

Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms

R Von Bernhardi, J Eugenín - Antioxidants & redox signaling, 2012 - liebertpub.com
Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …

Oxidative stress in Alzheimer's disease

Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …

Oxidant/antioxidant imbalance and the risk of Alzheimer's disease

AE Abdel Moneim - Current Alzheimer Research, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is the most common form of dementia characterized by
progressive loss of memory and other cognitive functions among older people. Senile …