Host defense mechanisms against Aspergillus fumigatus lung colonization and invasion
JJ Mackel, C Steele - Current opinion in microbiology, 2019 - Elsevier
The human lung is continually exposed to airborne conidia of the fungus Aspergillus
fumigatus (AF) and related species. The innate immune system efficiently eliminates inhaled …
fumigatus (AF) and related species. The innate immune system efficiently eliminates inhaled …
Innate lung defense during invasive aspergillosis: new mechanisms
JM Garth, C Steele - Journal of innate immunity, 2017 - karger.com
Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …
most lethal fungal infections known to man. Continued use of immunosuppressive agents …
Innate immunity and the role of epithelial barrier during Aspergillus fumigatus infection
E Svirshchevskaya, D Zubkov… - Current immunology …, 2012 - ingentaconnect.com
Fungi are the most important eukaryotic infective agents in Europe which largely overpass
parasite infections. Total number of people dying of fungal infection is increasing and this …
parasite infections. Total number of people dying of fungal infection is increasing and this …
[HTML][HTML] The innate immune response to Aspergillus fumigatus
V Balloy, M Chignard - Microbes and infection, 2009 - Elsevier
Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …
The innate immune response to Aspergillus fumigatus at the alveolar surface
A Margalit, K Kavanagh - FEMS microbiology reviews, 2015 - academic.oup.com
Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …
conidia which are inhaled by humans on a daily basis. When the immune system is …
[HTML][HTML] Bronchial epithelial cells on the front line to fight lung infection-causing Aspergillus fumigatus
Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …
Defense mechanisms of the airways against Aspergillus fumigatus: role in invasive aspergillosis
HF Kauffman, JFC Tomee - Fungal Allergy and Pathogenicity, 2002 - books.google.com
Fungal infections, including those by Aspergillus fumigatus, have become more prevalent in
recent years. Intensified medical treatment causing iatrogenic immunosuppression (eg in …
recent years. Intensified medical treatment causing iatrogenic immunosuppression (eg in …
[HTML][HTML] Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells
N Osherov - Frontiers in microbiology, 2012 - frontiersin.org
Aspergillus fumigatus is an opportunistic environmental mold that can cause severe allergic
responses in atopic individuals and poses a life-threatening risk for severely …
responses in atopic individuals and poses a life-threatening risk for severely …
New advances in invasive aspergillosis immunobiology leading the way towards personalized therapeutic approaches
Invasive aspergillosis (IA) remains a devastating disease in immune compromised patients
despite significant advances in our understanding of fungal virulence and host defense …
despite significant advances in our understanding of fungal virulence and host defense …
The pathobiology of Aspergillus fumigatus
JP Latgé - Trends in microbiology, 2001 - cell.com
Aspergillus fumigatus is the most prevalent airborne fungal pathogen in developed
countries, and in immunocompromised patients causes a usually fatal invasive aspergillosis …
countries, and in immunocompromised patients causes a usually fatal invasive aspergillosis …