In recent years, several lines of epidemiologic, clinical and experimental evidences have
been reported showing that estrogen hormones may be involved in malignant colorectal …

Carcinoma of the colon is common and its incidence varies according to the geographical
location and dietary habits. The aims of this paper are, first, to review the current …

Epidemiological data suggest a protective effect for estrogen replacement therapy on colon
cancer. The estrogen receptor (ER) is required for the action of estrogen. The ER-β isoform …

The concept that E2 exerts an effect on the gastrointestinal tract is not new and its actions on
intestinal mucosa have been investigated for at least three decades. An attempt to …

Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

Aim The role of oestrogen metabolism and action in colorectal cancer (CRC) is
controversial. An extensive review of the current literature, encompassing epidemiological …

Epidemiological studies describe estrogens as protectors in the development of colon
cancer in postmenopausal women treated with hormone replacement therapy. However, the …

We examined the expression of estrogen receptor (ER) messenger RNAs (ER-α, ER-β, and
ER-β isoforms) in colorectal tumor samples and corresponding normal mucosa, paying …

Colon cancer incidence and mortality rates are lower in females compared with males, and
numerous epidemiological studies suggest that estrogen replacement therapy (ERT) …

Estrogens have been implicated in the pathogenesis of various cancer types, including
colorectal carcinoma (CRC). Estrogen receptors such as ERα and ERβ activate intracellular …