[HTML][HTML] Neurokinin-1 receptor as a potential drug target for COVID-19 treatment

R Mehboob - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Abstract Novel Coronavirus infection (COVID-19) has become a pandemic in these days. It
is an acute respiratory and infectious disease with no known etiology and treatment. It is …

Aprepitant as a combinant with Dexamethasone reduces the inflammation via Neurokinin 1 Receptor Antagonism in severe to critical Covid-19 patients and …

R Mehboob, FJ Ahmad, A Qayyum, MA Rana… - Medrxiv, 2020 - medrxiv.org
Background Corona virus infection is a respiratory infection, compromising the normal
breathing in critical patients by damaging the lungs. Researches are ongoing to find an …

[HTML][HTML] Substance P/Neurokinin-1 receptor, trigeminal ganglion, latency, and coronavirus infection-is there any link?

R Mehboob, M Kurdi, A Bamaga, N Aldardeir… - Frontiers in …, 2021 - frontiersin.org
Novel Severe Acute Respiratory Syndrome-Corona Virus-2 infection (SARS-CoV-2) is an
acute respiratory and infectious disease. This perspective aims to provide a basic …

Effectiveness of aprepitant in post‐acute COVID19 syndrome

R Reinoso‐Arija, C López‐Ramírez… - Clinical Case …, 2021 - Wiley Online Library
Effectiveness of aprepitant in post‐acute COVID19 syndrome - Reinoso‐Arija - 2021 - Clinical
Case Reports - Wiley Online Library Skip to Article Content Skip to Article Information Wiley …

The rationale for angiotensin receptor neprilysin inhibitors in a multi-targeted therapeutic approach to COVID-19

A Bellis, C Mauro, E Barbato, B Trimarco… - International Journal of …, 2020 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19)
determines the angiotensin converting enzyme 2 (ACE2) down-regulation and related …

Safety and outcomes associated with the pharmacological inhibition of the kinin–kallikrein system in severe COVID-19

E Mansour, AC Palma, RG Ulaf, LC Ribeiro… - Viruses, 2021 - mdpi.com
Background: Coronavirus disease 19 (COVID-19) can develop into a severe respiratory
syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major …

Neuropilin‑1 as a new potential SARS‑CoV‑2 infection mediator implicated in the neurologic features and central nervous system involvement of COVID‑19

J Davies, HS Randeva, K Chatha… - Molecular …, 2020 - spandidos-publications.com
Infection by the severe acute respiratory syndrome (SARS) coronavirus‑2 (SARS‑CoV‑2) is
the cause of the new viral infectious disease (coronavirus disease 2019; COVID‑19) …

[PDF][PDF] Kinins and cytokines in COVID-19: a comprehensive pathophysiological approach

F van de Veerdonk, MG Netea, M van Deuren… - 2020 - pdfs.semanticscholar.org
Most striking observations in COVID-19 patients are the hints on pulmonary edema (also
seen on CT scans as ground glass opacities), dry cough, fluid restrictions to prevent more …

[HTML][HTML] Is neuropilin-1 the neuroimmune initiator of multi-system hyperinflammation in COVID-19?

K Saleki, P Alijanizadeh, A Azadmehr - Biomedicine & Pharmacotherapy, 2023 - Elsevier
A major immunopathological feature of Coronavirus disease-2019 (COVID-19) is excessive
inflammation in the form of “cytokine storm”. The storm is characterized by injurious levels of …

Tachykinins and the potential causal factors for post-COVID-19 condition

SJ Janket, DD Fraser, AE Baird, F Tamimi… - The Lancet …, 2023 - thelancet.com
The most prevalent symptoms of post-COVID-19 condition are pulmonary dysfunction,
fatigue and muscle weakness, anxiety, anosmia, dysgeusia, headaches, difficulty in …