A meta analysis on the utility of Anakinra in severe COVID-19 disease

AARM Hussein, R Sayad, A Abdelshafi, IA Hammam… - Cytokine, 2023 - Elsevier
Background and objective The most important presentation of COVID-19 is hyper
inflammatory condition and cytokine storm that occurs due to excessive increase of the …

Computational screening of potential drugs against COVID-19 disease: the Neuropilin-1 receptor as molecular target

H Charoute, Z Elkarhat, L Elkhattabi, E El Fahime… - Virusdisease, 2022 - Springer
The transmembrane receptor Neuropilin-1 (NRP-1) was reported to serve as a host cell
entry factor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the …

The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as potential …

H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …

Targeting neuropilins as a viable SARS‐CoV‐2 treatment

S Sarabipour, F Mac Gabhann - The FEBS Journal, 2021 - Wiley Online Library
The SARS‐CoV‐2 pandemic has significantly impacted global health. Research on viral
mechanisms, highly effective vaccines, and other therapies is in progress. Neuropilins have …

Therapeutic potential of the purinergic system in major depressive disorder associated with COVID-19

JLB Simões, ACL Galvan, ELM da Silva… - Cellular and Molecular …, 2023 - Springer
Neuroinflammation is closely related to the development of depression, since the latter is
caused, among other factors, by inflammatory processes, mainly related to the activation of …

[HTML][HTML] A potential therapeutic combination for treatment of COVID-19: synergistic effect of DPP4 and RAAS suppression

PP Khin, SH Cha, HS Jun, JH Lee - Medical hypotheses, 2020 - Elsevier
COVID-19, caused by the novel coronavirus SARS-CoV-2, is an abbreviated name for
coronavirus disease 2019. COVID-19 became a global pandemic in early 2020. It …

[HTML][HTML] Panax ginseng as a potential therapeutic for neurological disorders associated with COVID-19; Toward targeting inflammasome

SW Shin, IH Cho - Journal of Ginseng Research, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a highly infectious respiratory disease
caused by a severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). SARS-CoV-2 …

Anakinra—an interleukin-1 receptor antagonist for COVID-19

T Nguyen, L Dima, KC Willett - American Journal of Therapeutics, 2023 - journals.lww.com
Background: Coronavirus disease (COVID-19) caused by SARS-CoV-2 virus caused a
global pandemic in 2019. There are limited pharmacologic options available. The Food and …

Cholinergic dysfunction in COVID-19: frantic search and hoping for the best

EH Nadwa, HM Al-Kuraishy, AI Al-Gareeb… - Naunyn-Schmiedeberg's …, 2023 - Springer
A novel coronavirus known as severe acute respiratory syndrome coronavirus type 2 (SARS-
CoV-2) is a potential cause of acute respiratory infection called coronavirus disease 2019 …

[PDF][PDF] Pathophysiological mechanisms of disease severity in COVID-19: An update

MHB Siam, SMDM Abedin, A Ahmed… - J. Adv. Biotechnol …, 2020 - researchgate.net
The pandemic of COVID-19 has created a confounding global health crisis with more than
25 million cases and 870,000 deaths worldwide. The novel coronavirus, SARS-CoV-2 …