[HTML][HTML] Alternative mRNA fates identified in microRNA-associated transcriptome analysis

AP Carroll, N Tran, PA Tooney, MJ Cairns - BMC genomics, 2012 - Springer
Background MicroRNA (miRNA) are small non-coding RNA molecules which function as
nucleic acid-based specificity factors in the universal RNA binding complex known as the …

[HTML][HTML] Correlation of expression profiles between microRNAs and mRNA targets using NCI-60 data

YP Wang, KB Li - BMC genomics, 2009 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNAs affecting the expression of
target genes via translational repression or mRNA degradation mechanisms. With the …

Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP

J Meier, V Hovestadt, M Zapatka, A Pscherer… - RNA biology, 2013 - Taylor & Francis
MicroRNAs (miRNAs) are single-stranded, small, non-coding RNAs, which fine-tune protein
expression by degrading and/or translationally inhibiting mRNAs. Manipulation of miRNA …

The microRNA pathway and cancer

PB Kwak, S Iwasaki, Y Tomari - Cancer science, 2010 - Wiley Online Library
MicroRNAs (miRNAs) are∼ 22 nt long, non‐coding RNAs that guide post‐transcriptional
gene silencing of their target genes and regulate diverse biological processes including …

[HTML][HTML] The non-canonical aspects of microRNAs: many roads to gene regulation

CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

Cell-type-specific signatures of microRNAs on target mRNA expression

P Sood, A Krek, M Zavolan… - Proceedings of the …, 2006 - National Acad Sciences
Although it is known that the human genome contains hundreds of microRNA (miRNA)
genes and that each miRNA can regulate a large number of mRNA targets, the overall effect …

On the availability of microRNA-induced silencing complexes, saturation of microRNA-binding sites and stoichiometry

VK Mayya, TF Duchaine - Nucleic acids research, 2015 - academic.oup.com
Several authors have suggested or inferred that modest changes in microRNA expression
can potentiate or impinge on their capacity to mediate gene repression, and that doing so …

[HTML][HTML] Hunting the needle in the haystack: a guide to obtain biologically meaningful microRNA targets

M Karbiener, C Glantschnig, M Scheideler - International Journal of …, 2014 - mdpi.com
MicroRNAs (miRNAs) are endogenous small non-coding RNAs of~ 23 nucleotides in length
that form up a novel class of regulatory determinants, with a large set of target mRNAs …

[HTML][HTML] Insight into microRNA regulation by analyzing the characteristics of their targets in humans

Z Hu - BMC genomics, 2009 - Springer
Background microRNAs (miRNAs) are believed to regulate their targets through
posttranscriptional gene regulation and have the potential to silence gene expression via …

RNA silencing: Recent developments on miRNAs

FE Nicolas, S Lopez-Gomollon… - Recent Patents on …, 2009 - ingentaconnect.com
MicroRNAs (miRNAs) are small non-protein-coding transcripts that regulate gene
expression posttranscriptionally by pairing with target messenger RNAs (mRNAs). It is …