Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs …
JL Williams, S Borgo, I Hasan, E Castillo, F Traganos… - Cancer Research, 2001 - AACR
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NO-NSAIDs), consisting of a
known nonsteroidal anti-inflammatory drug (NSAID) and a nitric oxide (NO)-releasing group …
known nonsteroidal anti-inflammatory drug (NSAID) and a nitric oxide (NO)-releasing group …
NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property …
RK Yeh, J Chen, JL Williams, M Baluch… - Biochemical …, 2004 - Elsevier
The novel nitric oxide-donating nonsteroidal antiinflammatory drugs (NO-NSAIDs),
consisting of a traditional NSAID to which a NO releasing moiety is covalently attached, may …
consisting of a traditional NSAID to which a NO releasing moiety is covalently attached, may …
Nitric oxide–releasing aspirin and indomethacin are potent inhibitors against colon cancer in azoxymethane-treated rats: effects on molecular targets
CV Rao, BS Reddy, VE Steele, CX Wang, X Liu… - Molecular cancer …, 2006 - AACR
Nitric oxide–releasing nonsteroidal anti-inflammatory drugs (NO-NSAID) are promising
chemoprevention agents; unlike conventional NSAIDs, they seem free of appreciable …
chemoprevention agents; unlike conventional NSAIDs, they seem free of appreciable …
Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect
The novel nitric oxide (NO)-donating nonsteroidal anti-inflammatory drugs (NO-NSAIDs),
which are safer than their NSAID counterparts, inhibit the growth of colon cancer cells with …
which are safer than their NSAID counterparts, inhibit the growth of colon cancer cells with …
NO-releasing NSAIDs and colon cancer chemoprevention: a promising novel approach
B Rigas, JL Williams - International journal of oncology, 2002 - spandidos-publications.com
The chemoprevention of colon cancer, the second leading cause of cancer-related deaths in
the United States, has been pursued actively during the last two decades. Methodological …
the United States, has been pursued actively during the last two decades. Methodological …
Nitric-oxide-donating NSAIDs as agents for cancer prevention
B Rigas, K Kashfi - Trends in Molecular Medicine, 2004 - cell.com
Nitric-oxide-donating nonsteroidal anti-inflammatory drugs (NO–NSAIDs), which consist of
an NSAID with an NO-donating moiety covalently attached to it, promise to contribute …
an NSAID with an NO-donating moiety covalently attached to it, promise to contribute …
Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer
The earliest stages of colorectal cancer have been linked to inflammatory responses caused
by carcinogens, but the molecular signaling of various pro-and anti-inflammatory cytokines …
by carcinogens, but the molecular signaling of various pro-and anti-inflammatory cytokines …
Chemopreventive efficacy of naproxen and nitric oxide–naproxen in rodent models of colon, urinary bladder, and mammary cancers
VE Steele, CV Rao, Y Zhang, J Patlolla, D Boring… - Cancer Prevention …, 2009 - AACR
Nonsteroidal anti-inflammatory drugs (NSAID) have been highly effective in preventing
colon, urinary bladder, and skin cancer preclinically, and also in clinical trials of colon …
colon, urinary bladder, and skin cancer preclinically, and also in clinical trials of colon …
In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines
Background Nitric oxide-releasing nonsteroidal antiinflammatory drugs (NO-NSAIDs) are
reported to be safer than NSAIDs because of their lower gastric toxicity. We compared the …
reported to be safer than NSAIDs because of their lower gastric toxicity. We compared the …
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action
ML Smith, G Hawcroft, MA Hull - European journal of cancer, 2000 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit proliferation and induce apoptosis in
human colorectal cancer cells in vitro. It remains unclear whether individual NSAIDs act by …
human colorectal cancer cells in vitro. It remains unclear whether individual NSAIDs act by …