Incomplete delivery to the target cells is an obstacle for successful gene therapy
approaches. Here we show unexpected effects of incomplete targeting, by demonstrating …

Vascular endothelial growth factor-A (VEGF-A) has long been recognized as the key
regulator of vascular development and function in health and disease. VEGF is a secreted …

Vascular endothelial growth factor A (VEGF-A or VEGF) is a highly conserved secreted
signalling protein best known for its roles in vascular development and angiogenesis. Many …

Vascular endothelial growth factor (VEGF) has proven to be the most critical angiogenic
factor identified to date; its discovery has transformed the field of angiogenesis research …

Background Angiogenesis is a process by which new capillaries are formed from pre-
existing blood vessels in physiological (eg, exercise, wound healing) or pathological (eg …

Angiogenesis, the formation of new blood vessels from preexisting ones, is a central process
during normal development and during pathological repair. Vascular endothelial growth …

Vascular endothelial growth factor (VEGF) production by stromal fibroblasts plays an
important role in tumor angiogenesis. However, VEGF is also expressed by normal tissue …

Blood vessel expansion is driven by sprouting angiogenesis of endothelial cells, and is
essential for development, wound healing and disease. Membrane-localized vascular …

Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are
quintessential for the development and maintenance of blood and lymphatic vessels …

1. ABSTRACT A considerable progress has been made during the past years in elucidating
the molecular actors of angiogenesis. Vascular endothelial growth factor turned out to …