[HTML][HTML] Rationally designed ruthenium complexes for 1-and 2-photon photodynamic therapy

J Karges, S Kuang, F Maschietto, O Blacque… - Nature …, 2020 - nature.com
The use of photodynamic therapy (PDT) against cancer has received increasing attention
over recent years. However, the application of the currently approved photosensitizers (PSs) …

Rationally designed long-wavelength absorbing Ru (II) polypyridyl complexes as photosensitizers for photodynamic therapy

J Karges, F Heinemann, M Jakubaszek… - Journal of the …, 2020 - ACS Publications
The utilization of photodynamic therapy (PDT) for the treatment of various types of cancer
has gained increasing attention over the last decades. Despite the clinical success of …

Critical overview of the use of Ru (II) polypyridyl complexes as photosensitizers in one-photon and two-photon photodynamic therapy

F Heinemann, J Karges, G Gasser - Accounts of chemical …, 2017 - ACS Publications
Conspectus Photodynamic Therapy (PDT) is an emerging technique to treat certain types of
cancer, bacterial, fungal, and viral infections, and skin diseases. In past years, different …

Polymeric encapsulation of a ruthenium polypyridine complex for tumor targeted one-and two-photon photodynamic therapy

J Karges, J Li, L Zeng, H Chao… - ACS Applied Materials & …, 2020 - ACS Publications
Photodynamic therapy is a medical technique, which is gaining increasing attention to treat
various types of cancer. Among the investigated classes of photosensitizers (PSs), the use of …

Metal Complexes for Two‐Photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two‐Photon Photosensitization of Cancer Cells under Near‐IR …

LK McKenzie, IV Sazanovich… - … A European Journal, 2017 - Wiley Online Library
Photodynamic therapy (PDT) uses photosensitizers (PS) which only become cytotoxic upon
light‐irradiation. Transition‐metal complexes are highly promising PS due to long excited …

Harnessing ruthenium (II) as photodynamic agents: Encouraging advances in cancer therapy

J Liu, C Zhang, TW Rees, L Ke, L Ji, H Chao - Coordination Chemistry …, 2018 - Elsevier
Despite their past triumphs, platinum-based therapeutics remain limited by chemo-
resistance and severe side effects. As an alternative therapeutic modality which bypasses …

[HTML][HTML] Recent advances in noble metal complex based photodynamic therapy

Y Wu, S Li, Y Chen, W He, Z Guo - Chemical Science, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) utilizes light-activated photosensitizers (PSs) to generate toxic
species for therapeutics. It has become an emerging solution for cancer treatment because …

Highly charged ruthenium (II) polypyridyl complexes as lysosome‐localized photosensitizers for two‐photon photodynamic therapy

H Huang, B Yu, P Zhang, J Huang… - Angewandte Chemie …, 2015 - Wiley Online Library
Photodynamic therapy (PDT) is a noninvasive medical technique that has received
increasing attention over the last years and been applied for the treatment of certain types of …

Crossfire for two-photon photodynamic therapy with fluorinated ruthenium (II) photosensitizers

K Qiu, J Wang, C Song, L Wang, H Zhu… - … Applied Materials & …, 2017 - ACS Publications
Synergistic photodynamic therapy (PDT) that combines photosensitizers (PSs) to attack
different key sites in cancer cells is very attractive. However, the use of multiple PSs may …

Ru (II) containing photosensitizers for photodynamic therapy: A critique on reporting and an attempt to compare efficacy

MA Munegowda, A Manalac, M Weersink… - Coordination chemistry …, 2022 - Elsevier
Ruthenium (II)-based coordination complexes have emerged as photosensitizers (PSs) for
photodynamic therapy (PDT) in oncology as well as antimicrobial indications and have great …