Acknowledging the fallibilities of recalling events from more than three decades ago, the
recollection of Richard Carter's impact on the identification and development of Pfs25, a …

Among the Plasmodium falciparum surface antigens reported by Richard Carter and his
colleagues decades ago, Pfs230 is currently the target of the most advanced candidate for a …

In the early 1980s, Richard Carter was among the first researchers to identify the sexual
stage-specific Pfs48/45 protein, leading to the identification of target epitopes. Carter …

Transmission-blocking vaccines (TBVs), pioneered by Richard Carter and others, aim to
prevent parasite development in the mosquito vector and are a promising new tool for …

Pfs25 is a sexual stage antigen of Plasmodium falciparum that is expressed on the surface
of zygote and ookinete forms of the parasite. Monoclonal antibodies directed against native …

Each of the four epidermal growth factor (EGF)-like domains of the Plasmodium falciparum
sexual-stage antigen Pfs25 has been individually expressed as a yeast-secreted …

Antibodies to Pfs28 block Plasmodium falciparum transmission and when combined with
antibodies to Pfs25 provide synergy in blocking transmission. Pfs28 and Pfs25 are …

Background Vaccines against the sexual stages of the malarial parasite Plasmodium
falciparum are indispensable for controlling malaria and abrogating the spread of drug …

A crucial step has been made in the development of malaria vaccines. The first trial of SPf66
in Africa and the first outside Latin America has been completed in an area of very intense …

The origins of modern malariology can be traced back to a crucial observation first made by
Laveran one hundred and twelve years ago. His observation of a male gametocyte exfla …