Histamine and its receptors in the nervous system received recognition late in comparison to
the other aminergic transmitters, after the detection of histaminergic neurons in the posterior …

The G i/o protein-coupled histamine H 3 receptor is distributed throughout the central
nervous system including areas like cerebral cortex, hippocampus and striatum with the …

Alcohol use disorder is associated with several mental, physical, and social problems. Its
treatment is difficult and often requires a combination of pharmacological and behavioural …

The role of histamine in the central nervous system (CNS) is currently an area of great
interest. There are two major sources of amine in the human brain, namely mast cells and …

Expression and function of histamine H 4 R in central and peripheral nervous system have
been a matter of controversy for more than a decade. The scientific discussion is often …

Histamine H3 receptors were first described in the eighties but finally cloned four years ago.
They are G-protein coupled, mostly presynaptic, and are involved in the control of the …

The histamine H3 receptor, first described in 1983 as a histamine autoreceptor and later
shown to also function as a heteroreceptor that regulates the release of other …

Histamine has long been known to trigger allergic reactions and gastric acid secretion.
However, it was later discovered that, in the brain, histamine regulates basic homeostatic …

The brain histaminergic system is one of the diffuse modulatory neurotransmitter systems
which regulate neuronal activity in many brain areas. Studies on both rats and mice indicate …

The identification of histamine H3 (H3R) and H4 (H4R) receptors some years ago revived
interest in histamine research and exposed attractive perspectives for the potential …