Cancer is a common comorbidity of diabetic patients; however, little is known about the
effects that antidiabetic drugs have on tumors. We discovered that common classes of drugs …

Various plant polyphenols have been recognized as redox active molecules. This review
discusses some aspects of polyphenols' modes of redox action, corresponding structure …

Curcumin has been shown to prevent and inhibit carcinogen-induced tumorigenesis in
different organs of rodent carcinogenesis models. Our objective is to study global gene …

A major cell defense mechanism against oxidative and xenobiotic stress is mediated by the
Nrf2/Keap1 signaling pathway. The Nrf2/Keap1 pathway regulates gene expression of many …

Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Background Flavonoids exhibit both chemopreventive and chemotherapeutic activity for
multiple tumor types, however, their mechanisms of action are not well defined. Based on …

Frequent consumption of green tea, one of the most popular and widely consumed
beverages, has been known to protect against development of various cancers according to …

Hepatocellular carcinoma (HCC), considered to be one of the most lethal cancers with
almost> 1 million deaths reported annually worldwide, remains a devastating disease with …

The antioxidant responsive element (ARE) is a cis-acting regulatory element of genes
encoding phase II detoxification enzymes and antioxidant proteins, such as NAD (P) H …

The imbalance between reactive oxygen species (ROS) production and clearance causes
oxidative stress and ROS, which play a central role in regulating cell and tissue physiology …