The past, present and future of antimycotic combination therapy Vergangenheit, Gegenwart
und Zukunft der antimykotischen Kombina Page 1 mycoses 42, 355–370 (1999) Accepted …

The availability of new antifungal agents with novel mechanisms of action has stimulated
renewed interest in combination antifungal therapies. In particular, and despite the limited …

This portion of the antifungal review focuses on treatment rationale and suggestions,
including special populations such as the elderly, children, and pregnant and …

Invasive mycoses have become an important public health problem as their incidence has
increased dramatically in the last decades, while the discovery of the ideal antifungal agent …

The availability of new antifungal agents with unique mechanisms of action and improved
tolerability has widened the possibilities for the use of combination antifungal therapy for …

SUMMARY Between 1972 and 1977, the Southwest Oncology Group studied the following
three chemotherapy programs for the treatment of patients with advanced forms of mycosis …

Combination therapy is one way of improving the cure rate of onychomycosis. The LION
Study examined the efficacies of terbinafine and itraconazole. The Icelandic cohort of the …

Although the existence of fungi dates back a billion years, the history of medical mycology
and human mycoses as reviewed by Espinel-Ingroff began in the early 19th century in Italy …

Onychomycosis is the most common nail disease encountered in clinical practice. Its
importance extends well beyond aesthetics, often causing pain, difficulty with ambulation …

The story of antifungal agents has not been a stately procession from one development to
another. For many years there was no agent of value for systemic mycoses. Then, with the …