Introduction: Tanshinone IIA (Tan IIA), the major active lipophilic ingredient of Radix Salviae
Miltiorrhizae, exerts various therapeutic effects on the cardiovascular system. We aimed to …

Tanshinone IIA (TSIIA) is the major bioactive constituent of Salvia miltiorrhiza Bunge, a
Chinese herbal medicine, which has protective effects on myocardial ischemia/reperfusion …

Objective To determine the mechanism by which Tanshinone IIA (Tan IIA) relieves
myocardial ischemia reperfusion injury (MIRI) in rats via the PI3K/Akt/mTOR signaling …

Aim: To investigate the mechanisms underlying the protective effects of sodium tanshinone
IIA sulfonate (STS) in an ischemia-reperfusion (I/R)-induced rat myocardial injury model …

Context: Although there were reports on the protective functions of tanshinone IIA (TSA) on
rat myocardial ischemia, the exerting mechanism has not been completely clarified …

Objective The protective effect of sodium tanshinone IIA sulfonate (STS) pretreatment
against experimental myocardial ischemia/reperfusion (I/R) has been demonstrated …

Myocardial ischemia triggers an inflammatory reaction and oxidative stress that increases
apoptosis of myocardiocytes. It has been evidenced that tanshinone‑IIA (Tan‑IIA) protects …

Tanshinone, a natural compound found in the roots of Salvia miltiorrhiza, has been shown to
possess various pharmacological properties, including anti-inflammatory, antioxidant, and …

Sodium tanshinone IIA sulfonate (STS), a water-soluble derivative of tanshinone IIA, has
been used in traditional Chinese medicine for many years. Many experiments have …

Tanshinone IIA (Tan IIA) is a member of the major lipophilic components extracted from the
root of Salvia miltiorrhiza Bunge, which is currently used in China and other neighboring …