Piperacillin/tazobactam is a β-lactam/β-lactamase inhibitor combination with a broad
spectrum of antibacterial activity against most Gram-positive and Gram-negative aerobic …

(1) Background: Piperacillin-tazobactam represents the first-line option for treating infections
caused by full-or multi-susceptible Enterobacterales and/or Pseudomonas aeruginosa in …

We sought to study whether the better pharmacokinetic and pharmacodynamic (PK/PD)
properties of carbapenems and piperacillin/tazobactam, when the duration of infusion is …

A better dosing strategy can improve clinical outcomes for patients. We systematically
reviewed the literatures to determine whether any clinical benefits exist for piperacillin …

Introduction Ceftazidime is used for the treatment of many bacterial infections, including
severe P. aeruginosa infections. Like other beta-lactams, inter-individual variability in …

Methods: Blood samples (2–4 per child) were collected from 13 children ages 9 months to 6
years admitted to the pediatric intensive care unit who were receiving standard piperacillin …

The pharmacodynamics of dosage regimens of piperacillin alone or in combination with
tazobactam against piperacillin-resistant or-susceptible bacteria were studied in an in vitro …

The clinical efficacy of continuous infusion of piperacillin/tazobactam in critically ill patients
with microbiologically documented infections is currently unknown. We conducted a …

Ten volunteers received piperacillin (4 g), piperacillin (4 g) plus tazobactam (0.5 g)(Tazocin),
and ticarcillin (3 g) plus clavulanic acid (0.2 g)(Timentin) intravenously over 30 min in a …

Objectives We utilized the database of the Defining Antibiotic Levels in Intensive care unit
patients (DALI) study to statistically compare the pharmacokinetic/pharmacodynamic and …